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About the Authors:
Lokesh Bathala
Roles Conceptualization, Investigation, Project administration, Supervision, Writing - original draft, Writing - review & editing
* E-mail: [email protected]
Affiliation: Department of Neurology, Aster CMI Hospital, Bangalore, India
ORCID http://orcid.org/0000-0003-1918-5714
Venkataramana N. Krishnam
Roles Project administration, Visualization
Affiliation: Department of Neurosurgery, BGS Global Hospital, Bangalore, India
Hari Kishan Kumar
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing - review & editing
Affiliation: Department of Dermatology, Raja Rajeswari Medical College & Hospital, Bangalore, India
Vivekananda Neladimmanahally
Roles Resources
Affiliation: Department of Dermatology, Raja Rajeswari Medical College & Hospital, Bangalore, India
Umashankar Nagaraju
Roles Funding acquisition, Resources
Affiliation: Department of Dermatology, Raja Rajeswari Medical College & Hospital, Bangalore, India
Himanshu M. Kumar
Roles Data curation, Formal analysis, Visualization
Affiliation: Department of Public health, Rajiv Gandhi Institute of Public Health and Center for Disease Control, Bangalore, India
Johan A. Telleman
Roles Data curation, Software, Visualization
Affiliation: Department of Neurology and Clinical Neurophysiology, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands
Leo H. Visser
Roles Conceptualization, Methodology, Supervision, Validation, Writing - review & editing
Affiliation: Department of Neurology and Clinical Neurophysiology, Elisabeth-Tweesteden Hospital, Tilburg, The NetherlandsAbstract
Objective
Earlier studies have shown sonographic enlargement of the ulnar nerve in patients with Hansen’s neuropathy. The present study was performed to determine whether sonography or electrophysiological studies can detect the specific site of ulnar nerve pathology in leprosy.
Methods
Eighteen patients (thirty arms) with Hansen’s disease and an ulnar neuropathy of whom 66% had borderline tuberculoid (BT), 27% lepromatous leprosy (LL) and 7% mid-borderline (BB) leprosy were included in the study. Cross-sectional area (CSA) of ulnar nerve was measured every two centimeters from wrist to medial epicondyle and from there to axilla. All patients underwent standard motor and sensory nerve conduction studies of the ulnar nerve. Thirty age and sex matched controls underwent similar ulnar nerve CSA measurements and conduction studies.
Results
Ulnar nerve was clinically palpable in 19 of the 30 arms of patients. Motor and sensory nerve conduction studies of the ulnar nerve showed a reduced compound motor action potential and sensory nerve action potential amplitude in all patients. Motor Conduction Velocity (MCV) in patients were slower in comparison to controls, especially at the elbow and upper arm, but unable to exactly locate the site of the...