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Received Mar 22, 2017; Revised Jun 20, 2017; Accepted Jul 6, 2017
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1. Introduction
In recent years, there has been a general increase in consumption of herbal products and over the counter (OTC) health foods, nutraceuticals, and medicinal products from plants or other natural sources in developed countries [1]. This increase in the consumption of these herbal products has become a public health issue. Practices of cultivation, harvest, storage, processing, handling, and distribution together with the absence of effective sanitary control measures make natural products subject to a great variety of contamination. Of concern there also is the professionalism of practitioners in terms of quality, efficacy, and safety of their treatment methods and products from herbal and natural sources available in the market [2]. The interest in safety of these products is greatly due to the possible presence of pathogenic bacteria and toxigenic fungi that produce mycotoxins such as aflatoxins, excessive or banned pesticides, microbial contaminants, heavy metals, chemical toxins, or adulteration with conventional drugs [3]. The toxic effects of the aflatoxins include immunosuppressive, mutagenic, teratogenic, and hepatocarcinogenic activity.
A World Health Organization (WHO) survey indicated that about 70–80% of the world populations rely on nonconventional medicine mainly of herbal sources in their primary healthcare [4]. Most consumers and vendors believe and consider herbal products to be safe but microbial contamination in medicinal herbs is a concern, especially among the immunocompromised individuals as a result of their lowered immunity [5]. Medicinal herbal products have been reported to be...