A protruding nodule on the upper lip

Abstract

[...]human herpesvirus 8 immunohistochemical staining yielded negative results, and hence, a second excisional biopsy was attempted to confirm the diagnosis. [6] Histopathologically, epithelioid hemangioendothelioma is composed of cords, strands and solid aggregates of round, oval and polygonal cells with abundant pale eosinophilic cytoplasm, vesicular nuclei and inconspicuous nucleoli, embedded in a fibromyxoid or sclerotic stroma. [2] The risk of local recurrence or metastasis depends on the histologic features of the tumors, including nuclear atypia, increased mitotic activity, tumor cell spindling and necrosis.