It appears you don't have support to open PDFs in this web browser. To view this file, Open with your PDF reader
Abstract
Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet little is known about its biosynthesis and physiological functions. Extensive persulfide formation is apparent in cysteine-containing proteins in Escherichia coli and mammalian cells and is believed to result from post-translational processes involving hydrogen sulfide-related chemistry. Here we demonstrate effective CysSSH synthesis from the substrate
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details


1 Department of Environmental Health Sciences and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan
2 Department of Molecular Physiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
3 Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan; Department of Translational Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan
4 Environmental Biology Section, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
5 Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan
6 Department of Biological Science, Graduate School of Science, Osaka Prefecture University, Osaka, Japan
7 Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
8 Division of Cardiocirculatory Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan
9 Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan
10 Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan
11 Laboratory of Pharmacology, Showa Pharmaceutical University, Tokyo, Japan
12 Department of Genetics, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
13 Department of Molecular Immunology and Toxicology, National Institute of Oncology, Budapest, Hungary
14 Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital and Institute for Life Sciences, Southampton, UK
15 Department of Chemistry, Sonoma State University, Rohnert Park, CA, USA