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Received May 5, 2017; Accepted Sep 19, 2017
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
1. Introduction
Testicular cancer (TC) represents between 1% and 1.5% of male neoplasms. TC shows excellent cure rates. Germ cell tumors (GCTs) are classified as seminoma or nonseminoma. More than 90% of patients diagnosed with GCTs are cured, including 70% to 80% with advanced tumors who are treated with chemotherapy [1]. The main factors contributing to this outcome are careful staging at the time of diagnosis; adequate early treatment based on chemotherapeutic combinations, with or without radiotherapy and surgery; and very strict follow-up and salvage therapies [2]. Critically ill patients with TC may require intensive care due to different causes such as acute respiratory failure within a few days of initiation of the chemotherapy [3], postanesthetic recovery, infection, and sepsis; however no studies have reported the prognosis of this group of critically ill patients who require intensive care. Because of this limitation, we decided to perform the present study, aiming to evaluate the clinical characteristics and outcomes of critically ill patients with TC admitted to an oncological intensive care unit (ICU).
2. Methods
This was a prospective observational study of 60 consecutive critically ill cancer patients with TC admitted to the ICU of the Instituto Nacional de Cancerología (INCan), located in Mexico City, from February 2008 to February 2015. This study was approved by the Bioethics Committee of INCan, and the requirement for informed consent was waived (Rev/09/15).
Demographic, clinical, and laboratory data were collected during the first day of the ICU...