Abstract

Zika virus (ZIKV) is a mosquito-borne pathogen, and Aedes aegypti has been identified as the main vector of the disease. Other mosquito species in the Aedes and Culex genera have been suggested to have the potential for being competent vectors based on experimental exposition of mosquitoes to an infectious blood meal containing ZIKV. Here, we report the isolation in cell culture of ZIKV obtained from different body parts of wild-caught female mosquitoes (Ae. aegypti, Ae. vexans, Cx. quinquefasciatus, Cx. coronator, and Cx. tarsalis) and whole male mosquitoes (Ae. aegypti and Cx. quinquefasciatus) in Mexico. Importantly, this is the first report that shows the presence of the virus in the salivary glands of the wild-caught female mosquitoes species, Cx. coronator, Cx. tarsalis, and Ae. vexans. Our findings strongly suggest that all the species reported herein are potential vectors for ZIKV.

Details

Title
Zika Virus in Salivary Glands of Five Different Species of Wild-Caught Mosquitoes from Mexico
Author
Elizondo-Quiroga, Darwin 1   VIAFID ORCID Logo  ; Medina-Sánchez, Aarón 2 ; Sánchez-González, Jorge M 2 ; Kristen Allison Eckert 3 ; Villalobos-Sánchez, Erendira 1 ; Navarro-Zúñiga, Antonio Rigoberto 2 ; Sánchez-Tejeda, Gustavo 4 ; Correa-Morales, Fabián 4 ; González-Acosta, Cassandra 4 ; Arias, Carlos F 5   VIAFID ORCID Logo  ; López, Susana 5 ; del Ángel, Rosa María 6 ; Pando-Robles, Victoria 7   VIAFID ORCID Logo  ; Elizondo-Quiroga, Armando E 2 

1  Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara, Jalisco, Mexico 
2  Secretaria de Salud Jalisco, Guadalajara, Jalisco, Mexico 
3  Independent consultant in Ajijic, Jalisco, Mexico 
4  Dirección del Programa de Enfermedades Transmitidas por Vector, Centro Nacional de Programas Preventivos y Control de Enfermedades, Secretaría de Salud de México, Mexico City, Mexico 
5  Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico 
6  Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del IPN, México City, Mexico 
7  Instituto Nacional de Salud Pública, Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Cuernavaca, Morelos, Mexico 
Pages
1-7
Publication year
2018
Publication date
Jan 2018
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41598-017-18682-3
ProQuest document ID
1988113095
Copyright
© 2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.