Abstract

Despite recent advances in the assembly of organic nanotubes, conferral of sequence-defined engineering and dynamic response characteristics to the tubules remains a challenge. Here we report a new family of highly designable and dynamic nanotubes assembled from sequence-defined peptoids through a unique “rolling-up and closure of nanosheet” mechanism. During the assembly process, amorphous spherical particles of amphiphilic peptoid oligomers crystallize to form well-defined nanosheets before folding to form single-walled nanotubes. These nanotubes undergo a pH-triggered, reversible contraction–expansion motion. By varying the number of hydrophobic residues of peptoids, we demonstrate tuning of nanotube wall thickness, diameter, and mechanical properties. Atomic force microscopy-based mechanical measurements show peptoid nanotubes are highly stiff (Young’s Modulus ~13–17 GPa). We further demonstrate the precise incorporation of functional groups within nanotubes and their applications in water decontamination and cellular adhesion and uptake. These nanotubes provide a robust platform for developing biomimetic materials tailored to specific applications.

Details

Title
Designable and dynamic single-walled stiff nanotubes assembled from sequence-defined peptoids
Author
Jin, Haibao 1 ; Yan-Huai Ding 2   VIAFID ORCID Logo  ; Wang, Mingming 1 ; Yang, Song 3 ; Liao, Zhihao 4 ; Newcomb, Christina J 1 ; Wu, Xuepeng 5 ; Tang, Xian-Qiong 6 ; Li, Zheng 6 ; Lin, Yuehe 7 ; Feng, Yan 8 ; Tengyue Jian 1 ; Mu, Peng 9 ; Chun-Long, Chen 1 

 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; Institute of Rheological Mechanics, Xiangtan University, Xiangtan, Hunan, China 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, USA 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, China 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; School of Petroleum Engineering, State Key Laboratory of Heavy Oil Processing, China University of Petroleum (East China), Qingdao, China 
 Institute of Rheological Mechanics, Xiangtan University, Xiangtan, Hunan, China 
 School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, USA 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; College of Chemistry and Chemical Engineering, Linyi University, Linyi, Shandong, China 
 Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; Department of Mechanical Engineering and Materials Science and Engineering Program, State University of New York, Binghamton, NY, USA 
Pages
1-11
Publication year
2018
Publication date
Jan 2018
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1988934816
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.