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About the Authors:
Marcell Crispim
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing - original draft
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Flávia Silva Damasceno
Roles Conceptualization, Investigation, Methodology, Writing - original draft
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Agustín Hernández
Roles Investigation, Methodology, Writing - original draft
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
ORCID http://orcid.org/0000-0002-7884-8023
María Julia Barisón
Roles Investigation, Methodology
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Ismael Pretto Sauter
Roles Methodology
Affiliation: Immunobiology of Leishmania-Macrophage Interaction Laboratory, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
ORCID http://orcid.org/0000-0002-5824-445X
Raphael Souza Pavani
Roles Methodology
Affiliation: Special Laboratory of Cell Cycle, Center of Toxins, Immunology and Cell Signalling, Butantan Institute, São Paulo, SP, Brazil
ORCID http://orcid.org/0000-0002-7187-2995
Alexandre Santos Moura
Roles Methodology
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Elizabeth Mieko Furusho Pral
Roles Investigation, Methodology
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Mauro Cortez
Roles Formal analysis, Resources, Supervision
Affiliation: Immunobiology of Leishmania-Macrophage Interaction Laboratory, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
Maria Carolina Elias
Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision
Affiliation: Special Laboratory of Cell Cycle, Center of Toxins, Immunology and Cell Signalling, Butantan Institute, São Paulo, SP, Brazil
Ariel Mariano Silber
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing - original draft, Writing - review & editing
* E-mail: [email protected]
Affiliation: Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil
ORCID http://orcid.org/0000-0003-4528-4732Abstract
Trypanosoma cruzi, the etiological agent of Chagas disease, consumes glucose and amino acids depending on the environmental availability of each nutrient during its complex life cycle. For example, amino acids are the major energy and carbon sources in the...