Details
Title
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Author
Barbeira, Alvaro N 1
; Dickinson, Scott P 1 ; Bonazzola, Rodrigo 1 ; Zheng, Jiamao 1 ; Wheeler, Heather E 2
; Torres, Jason M 3 ; Torstenson, Eric S 4 ; Shah, Kaanan P 1 ; Garcia, Tzintzuni 5 ; Edwards, Todd L 6
; Stahl, Eli A 7 ; Huckins, Laura M 7 ; Aguet, François 8 ; Ardlie, Kristin G 8 ; Cummings, Beryl B 9 ; Gelfand, Ellen T 8 ; Getz, Gad 10 ; Kane, Hadley 8 ; Handsaker, Robert E 11 ; Huang, Katherine H 8 ; Kashin, Seva 11 ; Karczewski, Konrad J 9 ; Lek, Monkol 9 ; Li, Xiao 8 ; MacArthur, Daniel G 9 ; Nedzel, Jared L 8 ; Nguyen, Duyen T 8 ; Noble, Michael S 8 ; Segrè, Ayellet V 8 ; Trowbridge, Casandra A 8 ; Tukiainen, Taru 9 ; Abell, Nathan S 12 ; Balliu, Brunilda 13 ; Barshir, Ruth 14 ; Basha, Omer 14 ; Battle, Alexis 15 ; Bogu, Gireesh K 16 ; Brown, Andrew 17 ; Brown, Christopher D 18 ; Castel, Stephane E 19 ; Chen, Lin S 20 ; Chiang, Colby 21 ; Conrad, Donald F 22 ; Damani, Farhan N 15 ; Davis, Joe R 12 ; Delaneau, Olivier 17 ; Dermitzakis, Emmanouil T 17 ; Engelhardt, Barbara E 23 ; Eskin, Eleazar 24 ; Ferreira, Pedro G 25 ; Frésard, Laure 12 ; Gamazon, Eric R 26 ; Garrido-Martín, Diego 16 ; Gewirtz, Ariel D H 27 ; Gliner, Genna 28 ; Gloudemans, Michael J 29 ; Guigo, Roderic 30 ; Hall, Ira M 31 ; Han, Buhm 32 ; He, Yuan 33 ; Hormozdiari, Farhad 34 ; Howald, Cedric 17 ; Jo, Brian 27 ; Eun Yong Kang 34 ; Kim, Yungil 15 ; Kim-Hellmuth, Sarah 19 ; Lappalainen, Tuuli 19 ; Li, Gen 35 ; Li, Xin 13 ; Liu, Boxiang 36 ; Serghei Mangul 34 ; McCarthy, Mark I 37 ; McDowell, Ian C 38 ; Mohammadi, Pejman 19 ; Monlong, Jean 39 ; Montgomery, Stephen B 12 ; Muñoz-Aguirre, Manuel 40 ; Ndungu, Anne W 41 ; Nobel, Andrew B 42 ; Oliva, Meritxell 43 ; Ongen, Halit 17 ; Palowitch, John J 44 ; Panousis, Nikolaos 17 ; Papasaikas, Panagiotis 16 ; Park, YoSon 18 ; Parsana, Princy 15 ; Payne, Anthony J 41 ; Peterson, Christine B 45 ; Quan, Jie 46 ; Reverter, Ferran 47 ; Sabatti, Chiara 48 ; Saha, Ashis 15 ; Sammeth, Michael 49 ; Scott, Alexandra J 21 ; Shabalin, Andrey A 50 ; Sodaei, Reza 16 ; Stephens, Matthew 51 ; Stranger, Barbara E 52 ; Strober, Benjamin J 33 ; Sul, Jae Hoon 53 ; Tsang, Emily K 54 ; Urbut, Sarah 55 ; van de Bunt, Martijn 56 ; Wang, Gao 55 ; Wen, Xiaoquan 57 ; Wright, Fred A 58 ; Xi, Hualin S 46 ; Yeger-Lotem, Esti 59 ; Zappala, Zachary 12 ; Zaugg, Judith B 60 ; Yi-Hui, Zhou 58 ; Akey, Joshua M 61 ; Bates, Daniel 62 ; Chan, Joanne 63 ; Claussnitzer, Melina 64 ; Demanelis, Kathryn 20 ; Diegel, Morgan 62 ; Doherty, Jennifer A 65 ; Feinberg, Andrew P 66 ; Fernando, Marian S 43 ; Halow, Jessica 62 ; Hansen, Kasper D 67 ; Haugen, Eric 62 ; Hickey, Peter F 68 ; Hou, Lei 69 ; Farzana Jasmine 20 ; Ruiqi Jian 63 ; Jiang, Lihua 63 ; Johnson, Audra 62 ; Kaul, Rajinder 62 ; Kellis, Manolis 69 ; Kibriya, Muhammad G 20 ; Lee, Kristen 62 ; Jin Billy Li 63 ; Li, Qin 63 ; Lin, Jessica 70 ; Lin, Shin 71 ; Linder, Sandra 12 ; Linke, Caroline 43 ; Liu, Yaping 69 ; Maurano, Matthew T 72 ; Molinie, Benoit 8 ; Nelson, Jemma 62 ; Neri, Fidencio J 62 ; Park, Yongjin 69 ; Pierce, Brandon L 20 ; Rinaldi, Nicola J 69 ; Rizzardi, Lindsay F 73 ; Sandstrom, Richard 62 ; Skol, Andrew 52 ; Smith, Kevin S 12 ; Snyder, Michael P 63 ; Stamatoyannopoulos, John 74 ; Tang, Hua 63 ; Wang, Li 8 ; Wang, Meng 63 ; Nicholas Van Wittenberghe 8 ; Wu, Fan 43 ; Zhang, Rui 63 ; Nierras, Concepcion R 75 ; Branton, Philip A 76 ; Carithers, Latarsha J 77 ; Guan, Ping 76 ; Moore, Helen M 76 ; Rao, Abhi 76 ; Vaught, Jimmie B 76 ; Gould, Sarah E 78 ; Lockart, Nicole C 78 ; Casey, Martin 78 ; Struewing, Jeffery P 78 ; Volpi, Simona 78 ; Addington, Anjene M 79 ; Koester, Susan E 79 ; Little, A Roger 80 ; Brigham, Lori E 81 ; Hasz, Richard 82 ; Hunter, Marcus 83 ; Johns, Christopher 84 ; Johnson, Mark 85 ; Kopen, Gene 86 ; Leinweber, William F 86 ; Lonsdale, John T 86 ; McDonald, Alisa 86 ; Mestichelli, Bernadette 86 ; Myer, Kevin 83 ; Roe, Brian 83 ; Salvatore, Michael 86 ; Saboor Shad 86 ; Thomas, Jeffrey A 86 ; Walters, Gary 85 ; Washington, Michael 85 ; Wheeler, Joseph 84 ; Bridge, Jason 87 ; Foster, Barbara A 88 ; Gillard, Bryan M 88 ; Karasik, Ellen 88 ; Kumar, Rachna 88 ; Miklos, Mark 87 ; Moser, Michael T 88 ; Jewell, Scott D 89 ; Montroy, Robert G 89 ; Rohrer, Daniel C 89 ; Valley, Dana R 89 ; Davis, David A 90 ; Mash, Deborah C 90 ; Undale, Anita H 91 ; Smith, Anna M 92 ; Tabor, David E 92 ; Roche, Nancy V 92 ; McLean, Jeffrey A 92 ; Vatanian, Negin 92 ; Robinson, Karna L 92 ; Sobin, Leslie 92 ; Barcus, Mary E 93 ; Valentino, Kimberly M 92 ; Qi, Liqun 92 ; Hunter, Steven 92 ; Hariharan, Pushpa 92 ; Singh, Shilpi 92 ; Ki Sung Um 92 ; Matose, Takunda 92 ; Tomaszewski, Maria M 92 ; Barker, Laura K 94 ; Mosavel, Maghboeba 95 ; Siminoff, Laura A 94 ; Traino, Heather M 94 ; Flicek, Paul 96 ; Juettemann, Thomas 96 ; Ruffier, Magali 96 ; Sheppard, Dan 96 ; Taylor, Kieron 96 ; Trevanion, Stephen J 96 ; Zerbino, Daniel R 96 ; Craft, Brian 97 ; Goldman, Mary 97 ; Haeussler, Maximilian 97 ; Kent, W James 97 ; Lee, Christopher M 97 ; Paten, Benedict 97 ; Rosenbloom, Kate R 97 ; Vivian, John 97 ; Zhu, Jingchun 97 ; Nicolae, Dan L 1 ; Cox, Nancy J 4 ; Im, Hae Kyung 1
1 Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA
2 Department of Biology, Loyola University Chicago, Chicago, IL, USA; Department of Computer Science, Loyola University Chicago, Chicago, IL, USA
3 Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL, USA
4 Vanderbilt Genetic Institute, Vanderbilt University Medical Center, Nashville, TN, USA
5 Center for Research Informatics, The University of Chicago, Chicago, IL, USA
6 Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA
7 Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY, USA; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY, USA
8 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA
9 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
10 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Massachusetts General Hospital Cancer Center, Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
11 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Department of Genetics, Harvard Medical School, Boston, MA, USA
12 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA
13 Department of Pathology, Stanford University, Stanford, CA, USA
14 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, BenGurion University of the Negev, Beer-Sheva, Israel
15 Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA
16 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain
17 Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute for Genetics and Genomics in Geneva (iG3), University of Geneva, Geneva, Switzerland; Swiss Institute of Bioinformatics, Geneva, Switzerland
18 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
19 New York Genome Center, New York, NY, USA; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA
20 Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA
21 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA
22 Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
23 Department of Computer Science, Center for Statistics and Machine Learning, Princeton University, Princeton, NJ, USA
24 Department of Computer Science, University of California, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, CA, USA
25 Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal; Institute of Molecular Pathology and Immunology (IPATIMUP), University of Porto, Porto, Portugal
26 Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
27 Lewis Sigler Institute, Princeton University, Princeton, NJ, USA
28 Department of Operations Research and Financial Engineering, Princeton University, Princeton, NJ, USA
29 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA; Biomedical Informatics Program, Stanford University, Stanford, CA, USA
30 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain
31 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA
32 Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
33 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
34 Department of Computer Science, University of California, Los Angeles, CA, USA
35 Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA
36 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA; Department of Biology, Stanford University, Stanford, CA, USA
37 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK
38 Computational Biology & Bioinformatics Graduate Program, Duke University, Durham, NC, USA
39 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Human Genetics Department, McGill University, Montreal, QC, Canada
40 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Departament d’Estadística i Investigació Operativa, Universitat Politècnica de Catalunya, Barcelona, Spain
41 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK
42 Department of Statistics and Operations Research, University of North Carolina, Chapel Hill, NC, USA; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA
43 Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA; Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL, USA
44 Department of Statistics and Operations Research, University of North Carolina, Chapel Hill, NC, USA
45 Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
46 Computational Sciences, Pfizer Inc, Cambridge, MA, USA
47 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain
48 Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Department of Statistics, Stanford University, Stanford, CA, USA
49 Institute of Biophysics Carlos Chagas Filho (IBCCF), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil
50 Department of Psychiatry, University of Utah, Salt Lake City, UT, USA
51 Department of Statistics, The University of Chicago, Chicago, IL, USA; Department of Human Genetics, The University of Chicago, Chicago, IL, USA
52 Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA; Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL, USA; Center for Data Intensive Science, The University of Chicago, Chicago, IL, USA
53 Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
54 Department of Pathology, Stanford University, Stanford, CA, USA; Biomedical Informatics Program, Stanford University, Stanford, CA, USA
55 Department of Human Genetics, The University of Chicago, Chicago, IL, USA
56 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
57 Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
58 Bioinformatics Research Center and Departments of Statistics and Biological Sciences, North Carolina State University, Raleigh, NC, USA
59 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, BenGurion University of the Negev, Beer-Sheva, Israel; National Institute for Biotechnology in the Negev, Beer-Sheva, Israel
60 European Molecular Biology Laboratory, Heidelberg, Germany
61 Lewis Sigler Institute, Princeton University, Princeton, NJ, USA; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA
62 Altius Institute for Biomedical Sciences, Seattle, Washington, USA
63 Department of Genetics, Stanford University, Stanford, CA, USA
64 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; University of Hohenheim, Stuttgart, Germany
65 Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA
66 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins University School of Public Health, Baltimore, MD, USA
67 Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
68 Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
69 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA
70 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Medicine, University of Washington, Seattle, Washington, USA
71 Department of Genetics, Stanford University, Stanford, CA, USA; Division of Cardiology, University of Washington, Seattle, Washington, USA
72 Institute for Systems Genetics, New York University Langone Medical Center, New York, NY, USA
73 Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
74 Altius Institute for Biomedical Sciences, Seattle, Washington, USA; Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA
75 Office of Strategic Coordination, Division of Program Coordination, Planning and Strategic Initiatives, Office of the Director, NIH, Rockville, MD, USA
76 Biorepositories and Biospecimen Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA
77 Biorepositories and Biospecimen Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA; National Institute of Dental and Craniofacial Research, Bethesda, MD, USA
78 Division of Genomic Medicine, National Human Genome Research Institute, Rockville, MD, USA
79 Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, NIH, Bethesda, MD, USA
80 Division of Neuroscience and Behavior, National Institute on Drug Abuse, NIH, Bethesda, MD, USA
81 Washington Regional Transplant Community, Falls Church, VA, USA
82 Gift of Life Donor Program, Philadelphia, PA, USA
83 LifeGift, Houston, TX, USA
84 Center for Organ Recovery and Education, Pittsburgh, PA, USA
85 LifeNet Health, Virginia Beach, VA, USA
86 National Disease Research Interchange, Philadelphia, PA, USA
87 Unyts, Buffalo, NY, USA
88 Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY, USA
89 Van Andel Research Institute, Grand Rapids, MI, USA
90 Brain Endowment Bank, Miller School of Medicine, University of Miami, Miami, FL, USA
91 National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA
92 Biospecimen Research Group, Clinical Research Directorate, Leidos Biomedical Research, Inc., Rockville, MD, USA
93 Leidos Biomedical Research, Inc, Frederick, MD, USA
94 Temple University, Philadelphia, PA, USA
95 Department of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA
96 European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK
97 UCSC Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA
; Dickinson, Scott P 1 ; Bonazzola, Rodrigo 1 ; Zheng, Jiamao 1 ; Wheeler, Heather E 2
; Torres, Jason M 3 ; Torstenson, Eric S 4 ; Shah, Kaanan P 1 ; Garcia, Tzintzuni 5 ; Edwards, Todd L 6
; Stahl, Eli A 7 ; Huckins, Laura M 7 ; Aguet, François 8 ; Ardlie, Kristin G 8 ; Cummings, Beryl B 9 ; Gelfand, Ellen T 8 ; Getz, Gad 10 ; Kane, Hadley 8 ; Handsaker, Robert E 11 ; Huang, Katherine H 8 ; Kashin, Seva 11 ; Karczewski, Konrad J 9 ; Lek, Monkol 9 ; Li, Xiao 8 ; MacArthur, Daniel G 9 ; Nedzel, Jared L 8 ; Nguyen, Duyen T 8 ; Noble, Michael S 8 ; Segrè, Ayellet V 8 ; Trowbridge, Casandra A 8 ; Tukiainen, Taru 9 ; Abell, Nathan S 12 ; Balliu, Brunilda 13 ; Barshir, Ruth 14 ; Basha, Omer 14 ; Battle, Alexis 15 ; Bogu, Gireesh K 16 ; Brown, Andrew 17 ; Brown, Christopher D 18 ; Castel, Stephane E 19 ; Chen, Lin S 20 ; Chiang, Colby 21 ; Conrad, Donald F 22 ; Damani, Farhan N 15 ; Davis, Joe R 12 ; Delaneau, Olivier 17 ; Dermitzakis, Emmanouil T 17 ; Engelhardt, Barbara E 23 ; Eskin, Eleazar 24 ; Ferreira, Pedro G 25 ; Frésard, Laure 12 ; Gamazon, Eric R 26 ; Garrido-Martín, Diego 16 ; Gewirtz, Ariel D H 27 ; Gliner, Genna 28 ; Gloudemans, Michael J 29 ; Guigo, Roderic 30 ; Hall, Ira M 31 ; Han, Buhm 32 ; He, Yuan 33 ; Hormozdiari, Farhad 34 ; Howald, Cedric 17 ; Jo, Brian 27 ; Eun Yong Kang 34 ; Kim, Yungil 15 ; Kim-Hellmuth, Sarah 19 ; Lappalainen, Tuuli 19 ; Li, Gen 35 ; Li, Xin 13 ; Liu, Boxiang 36 ; Serghei Mangul 34 ; McCarthy, Mark I 37 ; McDowell, Ian C 38 ; Mohammadi, Pejman 19 ; Monlong, Jean 39 ; Montgomery, Stephen B 12 ; Muñoz-Aguirre, Manuel 40 ; Ndungu, Anne W 41 ; Nobel, Andrew B 42 ; Oliva, Meritxell 43 ; Ongen, Halit 17 ; Palowitch, John J 44 ; Panousis, Nikolaos 17 ; Papasaikas, Panagiotis 16 ; Park, YoSon 18 ; Parsana, Princy 15 ; Payne, Anthony J 41 ; Peterson, Christine B 45 ; Quan, Jie 46 ; Reverter, Ferran 47 ; Sabatti, Chiara 48 ; Saha, Ashis 15 ; Sammeth, Michael 49 ; Scott, Alexandra J 21 ; Shabalin, Andrey A 50 ; Sodaei, Reza 16 ; Stephens, Matthew 51 ; Stranger, Barbara E 52 ; Strober, Benjamin J 33 ; Sul, Jae Hoon 53 ; Tsang, Emily K 54 ; Urbut, Sarah 55 ; van de Bunt, Martijn 56 ; Wang, Gao 55 ; Wen, Xiaoquan 57 ; Wright, Fred A 58 ; Xi, Hualin S 46 ; Yeger-Lotem, Esti 59 ; Zappala, Zachary 12 ; Zaugg, Judith B 60 ; Yi-Hui, Zhou 58 ; Akey, Joshua M 61 ; Bates, Daniel 62 ; Chan, Joanne 63 ; Claussnitzer, Melina 64 ; Demanelis, Kathryn 20 ; Diegel, Morgan 62 ; Doherty, Jennifer A 65 ; Feinberg, Andrew P 66 ; Fernando, Marian S 43 ; Halow, Jessica 62 ; Hansen, Kasper D 67 ; Haugen, Eric 62 ; Hickey, Peter F 68 ; Hou, Lei 69 ; Farzana Jasmine 20 ; Ruiqi Jian 63 ; Jiang, Lihua 63 ; Johnson, Audra 62 ; Kaul, Rajinder 62 ; Kellis, Manolis 69 ; Kibriya, Muhammad G 20 ; Lee, Kristen 62 ; Jin Billy Li 63 ; Li, Qin 63 ; Lin, Jessica 70 ; Lin, Shin 71 ; Linder, Sandra 12 ; Linke, Caroline 43 ; Liu, Yaping 69 ; Maurano, Matthew T 72 ; Molinie, Benoit 8 ; Nelson, Jemma 62 ; Neri, Fidencio J 62 ; Park, Yongjin 69 ; Pierce, Brandon L 20 ; Rinaldi, Nicola J 69 ; Rizzardi, Lindsay F 73 ; Sandstrom, Richard 62 ; Skol, Andrew 52 ; Smith, Kevin S 12 ; Snyder, Michael P 63 ; Stamatoyannopoulos, John 74 ; Tang, Hua 63 ; Wang, Li 8 ; Wang, Meng 63 ; Nicholas Van Wittenberghe 8 ; Wu, Fan 43 ; Zhang, Rui 63 ; Nierras, Concepcion R 75 ; Branton, Philip A 76 ; Carithers, Latarsha J 77 ; Guan, Ping 76 ; Moore, Helen M 76 ; Rao, Abhi 76 ; Vaught, Jimmie B 76 ; Gould, Sarah E 78 ; Lockart, Nicole C 78 ; Casey, Martin 78 ; Struewing, Jeffery P 78 ; Volpi, Simona 78 ; Addington, Anjene M 79 ; Koester, Susan E 79 ; Little, A Roger 80 ; Brigham, Lori E 81 ; Hasz, Richard 82 ; Hunter, Marcus 83 ; Johns, Christopher 84 ; Johnson, Mark 85 ; Kopen, Gene 86 ; Leinweber, William F 86 ; Lonsdale, John T 86 ; McDonald, Alisa 86 ; Mestichelli, Bernadette 86 ; Myer, Kevin 83 ; Roe, Brian 83 ; Salvatore, Michael 86 ; Saboor Shad 86 ; Thomas, Jeffrey A 86 ; Walters, Gary 85 ; Washington, Michael 85 ; Wheeler, Joseph 84 ; Bridge, Jason 87 ; Foster, Barbara A 88 ; Gillard, Bryan M 88 ; Karasik, Ellen 88 ; Kumar, Rachna 88 ; Miklos, Mark 87 ; Moser, Michael T 88 ; Jewell, Scott D 89 ; Montroy, Robert G 89 ; Rohrer, Daniel C 89 ; Valley, Dana R 89 ; Davis, David A 90 ; Mash, Deborah C 90 ; Undale, Anita H 91 ; Smith, Anna M 92 ; Tabor, David E 92 ; Roche, Nancy V 92 ; McLean, Jeffrey A 92 ; Vatanian, Negin 92 ; Robinson, Karna L 92 ; Sobin, Leslie 92 ; Barcus, Mary E 93 ; Valentino, Kimberly M 92 ; Qi, Liqun 92 ; Hunter, Steven 92 ; Hariharan, Pushpa 92 ; Singh, Shilpi 92 ; Ki Sung Um 92 ; Matose, Takunda 92 ; Tomaszewski, Maria M 92 ; Barker, Laura K 94 ; Mosavel, Maghboeba 95 ; Siminoff, Laura A 94 ; Traino, Heather M 94 ; Flicek, Paul 96 ; Juettemann, Thomas 96 ; Ruffier, Magali 96 ; Sheppard, Dan 96 ; Taylor, Kieron 96 ; Trevanion, Stephen J 96 ; Zerbino, Daniel R 96 ; Craft, Brian 97 ; Goldman, Mary 97 ; Haeussler, Maximilian 97 ; Kent, W James 97 ; Lee, Christopher M 97 ; Paten, Benedict 97 ; Rosenbloom, Kate R 97 ; Vivian, John 97 ; Zhu, Jingchun 97 ; Nicolae, Dan L 1 ; Cox, Nancy J 4 ; Im, Hae Kyung 1
1 Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA
2 Department of Biology, Loyola University Chicago, Chicago, IL, USA; Department of Computer Science, Loyola University Chicago, Chicago, IL, USA
3 Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL, USA
4 Vanderbilt Genetic Institute, Vanderbilt University Medical Center, Nashville, TN, USA
5 Center for Research Informatics, The University of Chicago, Chicago, IL, USA
6 Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA
7 Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY, USA; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY, USA
8 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA
9 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
10 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Massachusetts General Hospital Cancer Center, Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
11 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Department of Genetics, Harvard Medical School, Boston, MA, USA
12 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA
13 Department of Pathology, Stanford University, Stanford, CA, USA
14 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, BenGurion University of the Negev, Beer-Sheva, Israel
15 Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA
16 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain
17 Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Institute for Genetics and Genomics in Geneva (iG3), University of Geneva, Geneva, Switzerland; Swiss Institute of Bioinformatics, Geneva, Switzerland
18 Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
19 New York Genome Center, New York, NY, USA; Department of Systems Biology, Columbia University Medical Center, New York, NY, USA
20 Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA
21 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA
22 Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
23 Department of Computer Science, Center for Statistics and Machine Learning, Princeton University, Princeton, NJ, USA
24 Department of Computer Science, University of California, Los Angeles, CA, USA; Department of Human Genetics, University of California, Los Angeles, CA, USA
25 Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal; Institute of Molecular Pathology and Immunology (IPATIMUP), University of Porto, Porto, Portugal
26 Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
27 Lewis Sigler Institute, Princeton University, Princeton, NJ, USA
28 Department of Operations Research and Financial Engineering, Princeton University, Princeton, NJ, USA
29 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA; Biomedical Informatics Program, Stanford University, Stanford, CA, USA
30 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain
31 McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA
32 Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
33 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
34 Department of Computer Science, University of California, Los Angeles, CA, USA
35 Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA
36 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Pathology, Stanford University, Stanford, CA, USA; Department of Biology, Stanford University, Stanford, CA, USA
37 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, UK
38 Computational Biology & Bioinformatics Graduate Program, Duke University, Durham, NC, USA
39 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Human Genetics Department, McGill University, Montreal, QC, Canada
40 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Departament d’Estadística i Investigació Operativa, Universitat Politècnica de Catalunya, Barcelona, Spain
41 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK
42 Department of Statistics and Operations Research, University of North Carolina, Chapel Hill, NC, USA; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA
43 Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA; Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL, USA
44 Department of Statistics and Operations Research, University of North Carolina, Chapel Hill, NC, USA
45 Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
46 Computational Sciences, Pfizer Inc, Cambridge, MA, USA
47 Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain
48 Department of Biomedical Data Science, Stanford University, Stanford, CA, USA; Department of Statistics, Stanford University, Stanford, CA, USA
49 Institute of Biophysics Carlos Chagas Filho (IBCCF), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil
50 Department of Psychiatry, University of Utah, Salt Lake City, UT, USA
51 Department of Statistics, The University of Chicago, Chicago, IL, USA; Department of Human Genetics, The University of Chicago, Chicago, IL, USA
52 Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, USA; Institute for Genomics and Systems Biology, The University of Chicago, Chicago, IL, USA; Center for Data Intensive Science, The University of Chicago, Chicago, IL, USA
53 Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
54 Department of Pathology, Stanford University, Stanford, CA, USA; Biomedical Informatics Program, Stanford University, Stanford, CA, USA
55 Department of Human Genetics, The University of Chicago, Chicago, IL, USA
56 Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
57 Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
58 Bioinformatics Research Center and Departments of Statistics and Biological Sciences, North Carolina State University, Raleigh, NC, USA
59 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, BenGurion University of the Negev, Beer-Sheva, Israel; National Institute for Biotechnology in the Negev, Beer-Sheva, Israel
60 European Molecular Biology Laboratory, Heidelberg, Germany
61 Lewis Sigler Institute, Princeton University, Princeton, NJ, USA; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA
62 Altius Institute for Biomedical Sciences, Seattle, Washington, USA
63 Department of Genetics, Stanford University, Stanford, CA, USA
64 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; University of Hohenheim, Stuttgart, Germany
65 Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA
66 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins University School of Public Health, Baltimore, MD, USA
67 Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
68 Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
69 The Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA
70 Department of Genetics, Stanford University, Stanford, CA, USA; Department of Medicine, University of Washington, Seattle, Washington, USA
71 Department of Genetics, Stanford University, Stanford, CA, USA; Division of Cardiology, University of Washington, Seattle, Washington, USA
72 Institute for Systems Genetics, New York University Langone Medical Center, New York, NY, USA
73 Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
74 Altius Institute for Biomedical Sciences, Seattle, Washington, USA; Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA
75 Office of Strategic Coordination, Division of Program Coordination, Planning and Strategic Initiatives, Office of the Director, NIH, Rockville, MD, USA
76 Biorepositories and Biospecimen Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA
77 Biorepositories and Biospecimen Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD, USA; National Institute of Dental and Craniofacial Research, Bethesda, MD, USA
78 Division of Genomic Medicine, National Human Genome Research Institute, Rockville, MD, USA
79 Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, NIH, Bethesda, MD, USA
80 Division of Neuroscience and Behavior, National Institute on Drug Abuse, NIH, Bethesda, MD, USA
81 Washington Regional Transplant Community, Falls Church, VA, USA
82 Gift of Life Donor Program, Philadelphia, PA, USA
83 LifeGift, Houston, TX, USA
84 Center for Organ Recovery and Education, Pittsburgh, PA, USA
85 LifeNet Health, Virginia Beach, VA, USA
86 National Disease Research Interchange, Philadelphia, PA, USA
87 Unyts, Buffalo, NY, USA
88 Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, NY, USA
89 Van Andel Research Institute, Grand Rapids, MI, USA
90 Brain Endowment Bank, Miller School of Medicine, University of Miami, Miami, FL, USA
91 National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA
92 Biospecimen Research Group, Clinical Research Directorate, Leidos Biomedical Research, Inc., Rockville, MD, USA
93 Leidos Biomedical Research, Inc, Frederick, MD, USA
94 Temple University, Philadelphia, PA, USA
95 Department of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA
96 European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK
97 UCSC Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA
Pages
1-20
Publication year
2018
Publication date
May 2018
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2036170303
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.