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Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) resistance to antimicrobials may result in the increased risk of treatment failure. The objective of the study was to analyse in vitro MRSA susceptibility to vancomycin, linezolid, daptomycin, tigecycline, ceftaroline, dalbavancin, clindamycin, ciprofloxacin and trimethoprim/sulfamethoxazole. All MRSA strains isolated from hospitalised patients were analysed according to the current microbiological recommendations. Finally, a total of 124 MRSA strains were analysed; all were susceptible to tested antibiotics. Dalbavancin had the lowest minimum inhibitory concentration (MIC), and vancomycin the highest MIC value. There were 28/124 strains of MRSA susceptible for clindamycin, 36/124 for ciprofloxacin and 121/124 for trimethoprim/sulfamethoxazole. Dalbavancin was the most effective antimicrobial in our study.

Details

Title
In vitro analysis of the minimal inhibitory concentration values of different generations of anti-methicillin-resistant Staphylococcus aureus antibiotics
Author
Guzek, Aneta; Rybicki, Zbigniew; Tomaszewski, Dariusz
Publication year
2018
Publication date
Jan/Mar 2018
Publisher
Elsevier Limited
ISSN
02550857
e-ISSN
19983646
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2036399578
Copyright
Copyright Medknow Publications & Media Pvt. Ltd. Jan/Mar 2018