Abstract

CIViC is an expert crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer (www.civicdb.org) describing the therapeutic, prognostic, and diagnostic relevance of inherited and somatic variants of all types. CIViC is committed to open source code, open access content, public application programming interfaces (APIs), and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine.

Details

Title
CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer.
Author
Griffith, Malachi; Spies, Nicholas C; Krysiak, Kilannin; Coffman, Adam C; Mcmichael, Joshua F; Ainscough, Benjamin J; Rieke, Damian T; Danos, Arpad M; Kujan, Lynzey; Ramirez, Cody A; Wagner, Alex H; Skidmore, Zachary L; Liu, Connor J; Jones, Martin R; Bilski, Rachel L; Lesurf, Robert; Barnell, Erica K; Shah, Nakul M; Bonakdar, Melika; Trani, Lee; Matlock, Matthew; Ramu, Avinash; Campbell, Katie M; Spies, Gregory C; Graubert, Aaron P; Gangavarapu, Karthik; Eldred, James M; Larson, David E; Walker, Jason R; Good, Benjamin M; Wu, Chunlei; Su, Andrew I; Dienstmann, Rodrigo; Jones, Steven Jm; Bose, Ron; Spencer, David H; Wartman, Lukas D; Wilson, Richard K; Mardis, Elaine R; Griffith, Obi L
University/institution
Cold Spring Harbor Laboratory Press
Section
New Results
Publication year
2016
Publication date
Sep 1, 2016
Publisher
Cold Spring Harbor Laboratory Press
ISSN
2692-8205
Source type
Working Paper
Language of publication
English
ProQuest document ID
2070503801
Copyright
�� 2016. This article is published under http://creativecommons.org/licenses/by/4.0/ (���the License���). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.