Preoperative controlling nutritional status (CONUT) score as a predictor of long-term outcome after curative resection followed by adjuvant chemotherapy in stage II-III gastric Cancer

Abstract

According to the manufacturer’s instructions, the cutoff values for elevated concentrations of serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19–9 and CA 72–4 were 5 ng/mL, 27 U/mL, and 5 U/mL, respectively. According to the nutritional status in CONUT score, the patients were divided into four groups: none (261 patients, 37.4%), light (396 patients, 56.8%), moderate (39 patients, 5.6%), and severe (1 patients, 0.1%) (Table 1; Fig. 1). [...]in recent years, it has been well acceptable that malnutrition is associated with poor clinical outcomes [24]. [...]clinicians also continue to seek reliable biomarkers for identifying cancer-associated malnutrition and improving the clinical management. [...]it was a retrospective single-center rather than multicenter study. [...]there might be potential selection bias for the inclusion of patients.