Rectal perforation following paclitaxel and carboplatin chemotherapy for advanced ovarian cancer: a case report and review of the literature

Abstract

* Case report * Open Access * Open Peer Review Rectal perforation following paclitaxel and carboplatin chemotherapy for advanced ovarian cancer: a case report and review of the literature * Sujen Jayakody1Email authorView ORCID ID profile, * Danette Bianca Wright1, * Corrina Chiong1, * Mona Liu1, * Clare Bouffler1 and * Toufic El-Khoury1 Journal of Medical Case Reports2018 12:221 https://doi.org/10.1186/s13256-018-1759-z © The Author(s). A systematic review of the literature (MEDLINE, Embase, Google Scholar) found only one other case report of rectal perforation following combination chemotherapy with paclitaxel and carboplatin in a patient with lung cancer [8]. [8] Rectal perforation in a patient treated with combination chemotherapy for lung cancer Lung cancer Gan To Kagaku Ryoho 36(2):301–4 2009 1 de Haan and van den Berg [4] Colonic perforation secondary to taxol therapy: an unusual presentation Ovarian cancer Onkologie 29(11):541–2 2006 1 Rose and Piver [5] Intestinal perforation secondary to paclitaxel Ovarian cancer Gynecologic Oncology 57(2):270–2 1995 3 Seewaldt et al. [10] Paclitaxel (Taxol) treatment for refractory ovarian cancer: phase II clinical trial Ovarian cancer Am J Obstet Gynecol 170(6):1666–70 1994 4 Carter and Durfee [7] A case of bowel perforation after neoadjuvant chemotherapy for advanced epithelial ovarian cancer Ovarian cancer Gynecologic Oncology 107(3):586–9 2007 1 Table 1 indicates the number of cases of colonic perforation mentioned in the literature following treatment with paclitaxel.