Abstract

Background

Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.

Results

In this study, we present circPrimer, which allows users to search, annotate, and visualize circRNAs. Additionally, circPrimer enables users to extract the spliced sequences and genomic sequences of any circRNA, including novel circRNAs. Furthermore, circPrimer help users to design primers for circRNAs and to determine the specificity of the circRNA primers.

Conclusions

CircPrimer is a user-friendly tool for exploring circRNAs that does not require special user skills.

Details

Title
CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers
Author
Zhong, Shanliang; Wang, Jinyan; Zhang, Qian; Xu, Hanzi; Feng, Jifeng
Publication year
2018
Publication date
2018
Publisher
BioMed Central
e-ISSN
14712105
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2090435324
Copyright
Copyright © 2018. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and conditions, you may use this content in accordance with the terms of the License.