Abstract

Background: Platelets are considered an important source of prothrombotic agents associated with inflammation in cancer related diseases. We aimed to compare the diagnostic accuracy of the platelet distribution width (PDW) and CA19-9 in resectable pancreas cancer. Method: A total of 83 stage-1 and 2 pancreatic adenocarcinoma (PAC) patients, and 85 age and sex-matched healthy participants were included in the study. All preoperative patient data, including PDW and CA19-9 were analyzed in terms of sensitivity, specificity, positive and negative predictive values, likelihood ratios, and diagnostic accuracy. Results: Demographic features were not significantly different among the groups. Platelet distribution width and CA19-9 were significantly higher in PAC compared to control group (p= 0.0001). Diagnostically, the sensitivity and specificity were 79% and 85% for PDW, while 78% and 91% for CA19-9. Diagnostic accuracy was measured by the area under the ROC curve, and PDW differs significantly (p

Details

Title
Comparison of Platelet Distribution Width and CA19-9 in Resectable Pancreas Cancer
Author
Kemal Turker Ulutas; Inanc Samil Sarici; Arpaci, Abdullah
Pages
210-213
Publication year
2018
Publication date
2018
Publisher
Academy of Medical Sciences of Bosnia and Herzegovina
ISSN
0350199X
e-ISSN
19865961
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2091233300
Copyright
© 2018. This work is licensed under http://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.