Abstract
Background: Malignant peripheral nerve sheath tumors (MPNSTs) constitute a group of soft tissue neoplasm with neuroectodermal origin. Most cases are small at presentation and only some have been described reaching giant dimensions. Case Description: We report two cases that were diagnosed and treated as giant MPNST of the scalp. Both patients had extensive lesion on the head with intracranial infiltration. Microsurgical resection was indicated and a vascularized free flap was used to cover the defect. During follow-up the tumors recurred and further surgical excision treatment by adjuvant radiation therapy was performed. Conclusion: MPNSTs of the scalp are rare neoplasm of the peripheral nervous system. They are aggressive lesion that can recur and their management requires a multimodality approach.
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Details
1 Department of Neurosurgery, Dharmais National Cancer Hospital, Jakarta
2 Department of Plastic Surgery, Dharmais National Cancer Hospital, Jakarta
3 Department of Neurology, Dharmais National Cancer Hospital, Jakarta
4 Department of Pathology Anatomy, Dharmais National Cancer Hospital, Jakarta
5 Department of Neurosurgery and Oncology & Stem Cell Working Group, Universitas Padjadjaran, Bandung