Abstract

The canonical model of sex-chromosome evolution predicts that, as recombination is suppressed along sex chromosomes, gametologs will progressively differentiate, eventually becoming heteromorphic. However, there are numerous examples of homomorphic sex chromosomes across the tree of life. This homomorphy has been suggested to result from frequent sex-chromosome turnovers, yet we know little about which forces drive them. Here, we describe an extremely fast rate of turnover among 28 species of Ranidae. Transitions are not random, but converge on several chromosomes, potentially due to genes they harbour. Transitions also preserve the ancestral pattern of male heterogamety, in line with the ‘hot-potato’ model of sex-chromosome transitions, suggesting a key role for mutation-load accumulation in non-recombining genomic regions. The importance of mutation-load selection in frogs might result from the extreme heterochiasmy they exhibit, making frog sex chromosomes differentiate immediately from emergence and across their entire length.

Details

Title
A rapid rate of sex-chromosome turnover and non-random transitions in true frogs
Author
Jeffries, Daniel L 1   VIAFID ORCID Logo  ; Lavanchy, Guillaume 1 ; Sermier, Roberto 1 ; Sredl, Michael J 2 ; Miura, Ikuo 3 ; Borzée, Amaël 4   VIAFID ORCID Logo  ; Barrow, Lisa N 5 ; Canestrelli, Daniele 6   VIAFID ORCID Logo  ; Pierre-André Crochet 7 ; Dufresnes, Christophe 1 ; Fu, Jinzhong 8 ; Wen-Juan, Ma 1 ; Constantino Macías Garcia 9   VIAFID ORCID Logo  ; Ghali, Karim 1 ; Nicieza, Alfredo G 10 ; Ryan P O’Donnell 2 ; Rodrigues, Nicolas 1   VIAFID ORCID Logo  ; Romano, Antonio 11 ; Martínez-Solano, Íñigo 12 ; Stepanyan, Ilona 13 ; Zumbach, Silvia 14 ; Brelsford, Alan 15 ; Perrin, Nicolas 1   VIAFID ORCID Logo 

1  Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland 
2  Arizona Game and Fish Department, 5000 W. Carefree Highway, Phoenix, AZ, USA 
3  Amphibian Research Center, Hiroshima University, Higashi-Hiroshima, Japan 
4  Division of EcoScience and Department of Life Sciences, Ewha Womans University, Seoul, Republic of Korea 
5  Museum of Southwestern Biology, MSC03 2020, 1 University of New Mexico, Albuquerque, NM, USA 
6  Department of Ecological and Biological Science, University of Tuscia, Viterbo, Italy 
7  CEFE, CNRS, University Montpellier, University Paul Valéry Montpellier 3, EPHE, IRD, Montpellier, France 
8  Department of Integrative Biology, University of Guelph, Guelph, ON, Canada 
9  Instituto de Ecología, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City, Mexico City, Mexico 
10  Research Unit of Biodiversity, UO-CSIC-PA, Mieres, Spain; Department of Biology of Organisms and Systems, Universidad de Oviedo, Mieres, Spain 
11  Consiglio Nazionale delle Ricerche, Istituto per i sistemi agricoli e forestali del mediterraneo, Via Patacca 84, Ercolano, NA, Italy; MUSE - Museo delle Scienze, Sezione di Zoologia dei Vertebrati, corso del Lavoro e della Scienza 3, Trento, Italy 
12  Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales, CSIC, Madrid, Spain 
13  Scientific Center of Zoology and Hydroecology, National Academy of Science, Republic of Armenia, Yerevan, Armenia 
14  Info Fauna - karch, UniMail, Bellevaux 51, Neuchâtel, Switzerland 
15  Evolution, Ecology, and Organismal Biology Department, University of California Riverside, Riverside, CA, USA 
Pages
1-11
Publication year
2018
Publication date
Oct 2018
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41467-018-06517-2
ProQuest document ID
2116608159
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.