Abstract

A complex system can be represented and analyzed as a network, where nodes represent the units of the network and edges represent connections between those units. For example, a brain network represents neurons as nodes and axons between neurons as edges. In many networks, some nodes have a disproportionately high number of edges as well as many edges between each other and are referred to as the “rich club”. In many different networks, the nodes of this club are assumed to support global network integration. Here we show that another set of nodes, which have edges diversely distributed across the network, form a “diverse club”. The diverse club exhibits, to a greater extent than the rich club, properties consistent with an integrative network function—these nodes are more highly interconnected and their edges are more critical for efficient global integration. Finally, these two clubs potentially evolved via distinct selection pressures.

Details

Title
The diverse club
Author
Bertolero, M A 1 ; Yeo, B T T 2 ; M D’Esposito 3 

 Helen Wills Neuroscience Institute and Department of Psychology, University of California Berkeley, Berkeley, CA, USA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA 
 Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore; Clinical Imaging Research Centre, National University of Singapore, Singapore, Singapore; Singapore Institute for Neurotechnology, National University of Singapore, Singapore, Singapore; Memory Networks Programme, National University of Singapore, Singapore, Singapore 
 Helen Wills Neuroscience Institute and Department of Psychology, University of California Berkeley, Berkeley, CA, USA 
Pages
1-11
Publication year
2017
Publication date
Nov 2017
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2127937635
Copyright
© 2017. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.