Abstract

Improving influenza vaccine efficacy is a priority to reduce the burden of influenza-associated morbidity and mortality. By careful selection of individuals based on health we show sustained response to influenza vaccination in older adults. Sustaining health in aging could be an important player in maintaining immune responses to influenza vaccination.

Trial registration

NCT03266237. Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266237.

Details

Title
Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
Author
Camous, Xavier; Visan, Lucian; Crystal Tan Tze Ying; Brian AbelShwe Zin Nyunt; Narang, Vipin; Poidinger, Michael; Carre, Christophe; Sesay, Sanie; Bosco, Nabil; Burdin, Nicolas; Tambyah, Paul Anantharajah; Ng, Tze Pin; Anis Larbi
Publication year
2018
Publication date
2018
Publisher
BioMed Central
e-ISSN
1742-4933
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s12979-018-0137-4
ProQuest document ID
2135006006
Copyright
Copyright © 2018. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.