Details
Title
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
Author
Becker, Jordan R 1 ; Cuella-Martin, Raquel 1 ; Barazas, Marco 2 ; Liu, Rui 3 ; Oliveira, Catarina 1
; Oliver, Antony W 4
; Bilham, Kirstin 1 ; Holt, Abbey B 5 ; Blackford, Andrew N 6 ; Heierhorst, Jörg 7
; Jonkers, Jos 2 ; Rottenberg, Sven 8
; J Ross Chapman 1
1 Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
2 Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands
3 St. Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia
4 Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, UK
5 MRC Brain Network Dynamics Unit, Department of Pharmacology, University of Oxford, Oxford, UK
6 Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK; CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK
7 St. Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia; Department of Medicine at St. Vincent’s Hospital, Melbourne Medical School, The University of Melbourne, Fitzroy, VIC, Australia
8 Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
; Oliver, Antony W 4
; Bilham, Kirstin 1 ; Holt, Abbey B 5 ; Blackford, Andrew N 6 ; Heierhorst, Jörg 7
; Jonkers, Jos 2 ; Rottenberg, Sven 8
; J Ross Chapman 1
1 Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK
2 Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands
3 St. Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia
4 Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, UK
5 MRC Brain Network Dynamics Unit, Department of Pharmacology, University of Oxford, Oxford, UK
6 Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK; CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, UK
7 St. Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia; Department of Medicine at St. Vincent’s Hospital, Melbourne Medical School, The University of Melbourne, Fitzroy, VIC, Australia
8 Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
Pages
1-12
Publication year
2018
Publication date
Dec 2018
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2157866181
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.