Abstract

The aim of the study was an ultrasound assessment of distal interphalangeal (DIP) joint enthesopathy in patients with nail psoriasis. Altogether, 72 patients with nail psoriasis (41 with psoriasis and 31 with psoriatic arthritis) and 30 people in the control group participated in the study. In total, 1014 nails were examined. The thickness of DIP digital extensor tendons in the groups of patients with psoriasis (Ps) and psoriatic arthritis (PsA) was correlated with the nail bed thickness (r = 0.316, p = 0.027 vs. r = 0.402, p = 0.031, respectively) and with the thickness of the nail matrix in patients with psoriasis (r = 0.421, p = 0.012). The linear regression model showed the tendon thickness in Ps patients to be affected by the nail bed thickness, duration of psoriasis and the thickness of the nail matrix, whereas in PsA patients it was found to be significantly affected by duration of psoriasis and of arthritis, the nail bed thickness, CRP concentration and the swollen joint count. Our findings may indicate the role of the nail-tendon apparatus changes in the PsA development and they emphasise the justifiability of US examinations in patients with psoriasis direct assessment of morphological changes in nails as potential predictors of PsA development.

Details

Title
Distal interphalangeal joint extensor tendon enthesopathy in patients with nail psoriasis
Author
Krajewska-Włodarczyk Magdalena 1   VIAFID ORCID Logo  ; Owczarczyk-Saczonek Agnieszka 2 ; Placek Waldemar 2 ; Wojtkiewicz Maja 3 ; Wiktorowicz Andrzej 4 ; Wojtkiewicz, Joanna 5 

1  Municipal Hospital in Olsztyn, Department of Rheumatology, Olsztyn, Poland; University of Warmia and Mazury, Department of Internal Medicine, School of Medicine, Collegium Medicum, Olsztyn, Poland (GRID:grid.412607.6) (ISNI:0000 0001 2149 6795); University of Warmia and Mazury, Department of Pathophysiology, School of Medicine, Collegium Medicum, Olsztyn, Poland (GRID:grid.412607.6) (ISNI:0000 0001 2149 6795) 
2  University of Warmia and Mazury, Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, Olsztyn, Poland (GRID:grid.412607.6) (ISNI:0000 0001 2149 6795) 
3  Faculty of Earth Sciences, Department of Geomatics and Cartography Nicolaus Copernicus University, Torun, Poland (GRID:grid.5374.5) (ISNI:0000 0001 0943 6490); DRAMIŃSKI S.A. Ultrasound Scanners, Olsztyn, Poland (GRID:grid.5374.5) 
4  DRAMIŃSKI S.A. Ultrasound Scanners, Olsztyn, Poland (GRID:grid.5374.5) 
5  University of Warmia and Mazury, Department of Pathophysiology, School of Medicine, Collegium Medicum, Olsztyn, Poland (GRID:grid.412607.6) (ISNI:0000 0001 2149 6795); School of Medicine, Collegium Medicum, University of Warmia and Mazury, Laboratory for Regenerative Medicine, 10-900, Olsztyn, Poland (GRID:grid.412607.6) (ISNI:0000 0001 2149 6795) 
Publication year
2019
Publication date
Dec 2019
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41598-019-39985-7
ProQuest document ID
2188587583
Copyright
This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.