Abstract

Grass waste was used for transform an inexpensive waste into health. Silver nanoparticles (AgNPs) have been synthesized using waste material (dried grass). The average size of silver nanoparticles observed in transmission electron images was estimated to be about 15 nm. The anticancer, antifungal and antibacterial effect of AgNPs were studied in vitro. The minimum inhibitory concentration of AgNPs against Pseudomonas aeruginosa and Acinetobacter baumannii was calculated about 3 µg/ml. The highest level of inhibitory effect of AgNPs against Fusarium solani was close to 90% at a concentration of 20 μg/ml of AgNPs. An inhibitory effect on the cancer cell growth is reach, by increasing the concentration of AgNPs to 5 µg/ml; the cancer cells’ survival decreases about 30%. Western results showed that the expression of Cyclin D1 protein of MCF-7 cell line decreased after treatment with the effective concentration of AgNPs.

Details

Title
Waste-grass-mediated green synthesis of silver nanoparticles and evaluation of their anticancer, antifungal and antibacterial activity
Author
Khatami, Mehrdad 1   VIAFID ORCID Logo  ; Sharifi, Iraj 2   VIAFID ORCID Logo  ; Nobre, Marcos A L 3   VIAFID ORCID Logo  ; Zafarnia, Niloofar 4 ; Aflatoonian, Mohammad R 5   VIAFID ORCID Logo 

1  Nanobioelectrochemistry Research Center, Bam University of Medical Sciences, Bam, Iran; Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 
2  Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran 
3  Department of Physics, School of Technology and Sciences, Sao Paulo State University – UNESP Presidente Prudente Brazil, Sao Paulo, Brazil 
4  Nanobioelectrochemistry Research Center, Bam University of Medical Sciences, Bam, Iran 
5  Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran 
End page
134
Publication year
2018
Publication date
Jun 2018
Publisher
Taylor & Francis Ltd.
ISSN
17518253
e-ISSN
17517192
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1080/17518253.2018.1444797
ProQuest document ID
2195309610
Copyright
© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.