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© 2017. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Purpose: High coronary calcium score (CCS) and post-procedural cardiac enzyme may be related with poor outcomes in patients with coronary stent implantation.

Methods: A total of 1,072 patients (63.2% male, mean age: 61.7±10.3 years) who underwent coronary multi-detect computed tomography at index procedure and follow-up coronary angiography (CAG) after drug-eluting stent (DES) were divided into two groups: those with and without target lesion revascularization (TLR; >50% reduction in luminal stent diameter or angina symptoms on follow-up CAG). The CCSs for predicting stent revascularization were elucidated.

Results: There were no significant differences between the two groups with regard to risk factors. The initial CCS was significantly higher in the TLR group (1,102.4±743.7 vs 345.8±51.05,P=0.04). After adjustment of significant factors for TLR, only CCS and post-procedural creatine kinase MB form (CK-MB) elevation were significant predictors of coronary artery TLR. Receiver operation curve revealed that >800 in CCS had 69% in sensitivity and 88% in specificity about predicting the TLR.

Conclusion: High CCS with post-procedural CK-MB might be the useful predictors for TLR after DES implantation.

Details

Title
High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
Author
Lee, Jae-Beom; Yun-Seok Choi; Woo-Baek, Chung; Kwon, Ami; Park, Chul-Soo; Man-Young, Lee
Pages
399-404
Section
Original Research
Publication year
2017
Publication date
2017
Publisher
Taylor & Francis Ltd.
ISSN
1176-9092
e-ISSN
1178-1998
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2224639832
Copyright
© 2017. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.