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© 2018. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Objective

Ultrasonography and cytology obtained by fine‐needle aspiration are part of the basic study of the thyroid nodule. Although they are not diagnostic in every case, they are cost‐effective methods that inform surgical treatment and its extent. The purpose of this study was to evaluate the accuracy of ultrasonography associated with fine‐needle aspiration to predict malignancy in nodular thyroid pathology.

Design and patients

We collected prospective data from patients undergoing thyroidectomy by single nodule or multinodular goitre between 2006 and 2016. A total of 417 patients were included. Ultrasounds were classified as suspected of malignancy if they had 2 or more of the following characteristics: hypoechogenicity, microcalcifications, intranodular central hypervascularization, irregular margins and poorly defined edges.

Measurements

Ultrasound and fine‐needle aspiration accuracy.

Results

In the postoperative study, 40% presented malignant pathology. 33% of patients with nonsuspicious ultrasound and 73% of those with suspicious ultrasound had malignant disease. Among patients with single nodule and suspicious ultrasound, the malignancy rate reached 80%. As for cytology, 100% of Bethesda VI patients, 88% of V, 63% of IV, 31% of III and 12% of II were found to have carcinoma. The combination of the 2 tests showed a high predictive value, particularly in cases of Bethesda IV cytology.

Conclusions

Thyroid cytology provides high predictive value of the presence of carcinoma. The predictive value of ultrasound is also high, mainly in the study of isolated nodules. The combination of the 2 tests results in increased diagnostic accuracy.

Details

Title
Diagnostic accuracy of ultrasound and fine‐needle aspiration in the study of thyroid nodule and multinodular goitre
Author
Fueyo, Antonio Rabal 1   VIAFID ORCID Logo  ; Magdalena Vilanova Serra 1 ; Enrique Lerma Puertas 2 ; Enrique Montserrat Esplugas 3 ; Pérez García, José Ignacio 1 ; Eugenia Mato Matute 4 ; De Leiva Hidalgo, Alberto 5 ; Antonio Moral Duarte 1 

 Department of General Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain 
 Department of Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain 
 Department of Radiology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain 
 Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER‐BBN), Av. Monforte de Lemos, 3‐5. Madrid, Spain; Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain 
 Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain 
Section
ORIGINAL ARTICLES
Publication year
2018
Publication date
Jul 2018
Publisher
John Wiley & Sons, Inc.
e-ISSN
23989238
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2266872244
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.