Abstract
Contrast-enhanced magnetic resonance imaging revealed an enhancing soft-tissue mass (1.9 cm × 2.1 cm × 2.5 cm) in posterior aspect of the third ventricle extending into the cerebral aqueduct bulging into the roof of the fourth ventricle leading to obstructive hydrocephalus [Figure 1]. Tumor cells were immunopositive for chromogranin (diffuse), focally for synaptophysin, and showed faint immunoreactivity for cytokeratin while negative for epithelial membrane antigen (EMA), glial fibrillary acidic protein, and neurofilament. [1] The WHO 2007 definition of PTPR is as follows: -”A rare neuroepithelial tumor of the pineal region in adults, characterized by papillary architecture and epithelial cytology, immunopositivity for cytokeratin, and ultrastructural features suggesting ependymal differentiation.”
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Details
1 Department of Radiation Oncology, Dr. B. R. A. IRCH, All India Institute of Medical Sciences, New Delhi
2 Department of Pathology, All India Institute of Medical Sciences, New Delhi
3 Department of Radiation Oncology, VMMC and Safdarjung Hospital, New Delhi