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Copyright © 2019 Anh Kieu Thi Tran et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/

Abstract

Background. Clonorchis sinensis/Opisthorchis viverrini and minute intestinal flukes (MIF) such as Haplorchis pumilio and H. taichui are fish-borne trematodes (FBT) that may coexist in regions where local people have a habit of eating raw fish like Vietnam. Responses to FBT should be verified according to the data on the distribution of these flukes. This study aims to explore the prevalence of different species of FBT and related factors among local people in a northern province of Vietnam. Methods. A cross-sectional study was conducted in Kim Son and Yen Khanh districts, Ninh Binh province, between March 2016 and March 2017. Four hundred people aged 15 years or older were interviewed and gave stool samples. The FBT eggs in faecal samples were enumerated by modified formalin-ether technique and identified by sequencing of the second internal transcribed spacer (ITS2) region. Result. Among the 400 persons, 19.5% were infected with FBT. On univariate analysis, eating raw fish was the main risk factor (odds ratios (OR)) of 6.769 (95% confidence interval (CI) of 2.655–17.259) followed by being of male gender (3.994 (CI95% 2.117–7.536)) and drinking alcohol (2.680 (CI95% 1.440–4.986)), respectively. There was no risk of increased infection among those living at home without hygienic latrines, those living close to rivers or having ponds, or those raising cats or dogs. By multivariate analysis, FBT infection was only related to the consumption of raw fish and gender. Seventy stool samples with a sufficient amount of faecal matter were subjected to DNA extraction, 42.85% of them yielded DNA production, and all were of Clonorchis sinensis. Conclusion. Results of the study showed the high prevalence of infection of fish-borne trematode, mostly C. sinensis among humans in Ninh Binh province. The prevention of FBT should be strengthened with programs detailed according to the distribution of FBT in different endemic areas.

Details

Title
Prevalence, Species Distribution, and Related Factors of Fish-Borne Trematode Infection in Ninh Binh Province, Vietnam
Author
Anh Kieu Thi Tran 1 ; Doan, Hoa Thuy 2 ; Do, Anh Ngoc 3   VIAFID ORCID Logo  ; Van Thi Nguyen 3 ; Su Xuan Hoang 4 ; Huong Thu Thi Le 5 ; Hoa Thi Hoang 6 ; Nam Hoang Le 7 ; Quyen Bao Thi Le 8 ; Tran-Anh Le 3   VIAFID ORCID Logo 

 Paediatric Department, Vinh Medical University, 161 Nguyen Phong Sac, Vinh, Nghe An, Vietnam 
 Ha Noi Police Hospital, Ha Noi, Vietnam 
 Department of Parasitology, Vietnam Military Medical University, 160 Phung Hung, Ha Dong, Ha Noi, Vietnam 
 Department of Microbiology and Pathogens, Institute of Biomedicine and Pharmacy, Vietnam Military Medical University, Ha Noi, Vietnam 
 Department of Microbiology and Biology, Ha Noi University of Pharmacy, 13 Le Thanh Tong, Ha Noi, Vietnam 
 Fundamental Medicine Department, Nam Dinh University of Nursing, 257 Han Thuyen Street, Nam Dinh City, Vietnam 
 Ninh Binh Centre for Disease Control, Le Thai To Road, Nam Thanh Ward, Ninh Binh City, Ninh Binh province, Vietnam 
 University of Science, National University of Ha Noi, Vietnam 
Editor
Bach X Tran
Publication year
2019
Publication date
2019
Publisher
John Wiley & Sons, Inc.
ISSN
23146133
e-ISSN
23146141
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2274644180
Copyright
Copyright © 2019 Anh Kieu Thi Tran et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/