Details
Title
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells
Author
Reitman, Zachary J 1 ; Paolella, Brenton R 2
; Bergthold, Guillaume 3 ; Pelton, Kristine 4 ; Becker, Sarah 4 ; Jones, Robert 4 ; Sinai, Claire E 5 ; Malkin, Hayley 6 ; Huang, Ying 4 ; Grimmet, Leslie 7 ; Herbert, Zachary T 7 ; Sun, Yu 6 ; Weatherbee, Jessica L 6 ; Alberta, John A 6 ; Daley, John F 8 ; Rozenblatt-Rosen, Orit 9 ; Condurat, Alexandra L 10 ; Kenin Qian 5 ; Khadka, Prasidda 6 ; Segal, Rosalind A 6 ; Haas-Kogan, Daphne 11 ; Filbin, Mariella G 10 ; Suva, Mario L 12
; Regev, Aviv 13 ; Stiles, Charles D 6 ; Kieran, Mark W 14 ; Goumnerova, Liliana 15
; Ligon, Keith L 16 ; Shalek, Alex K 17 ; Bandopadhayay, Pratiti 10 ; Beroukhim, Rameen 18
1 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA
2 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA
3 Hoffmann-La Roche, Product Development, Innovative Pediatric Oncology Drug Discovery, Basel, Switzerland; Centre Hospitalier Universitaire Strasbourg, Service Hématologie-Oncologie Pédiatrique, Strasbourg, France
4 Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA
5 Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA
6 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA
7 Molecular Biology Core Facilities, Dana-Farber Cancer Institute, Boston, MA, USA
8 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
9 Broad Institute of MIT and Harvard, Cambridge, MA, USA
10 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA
11 Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
12 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA
13 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Biology, Howard Hughes Medical Institute, Koch Institute, MIT, Cambridge, MA, USA
14 Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA; Bristol-Myers Squibb, Boston, Devens, MA, USA; Bristol-Myers Squibb, Lawrenceville, NJ, USA
15 Department of Neurosurgery, Boston Children’s Hospital, Boston, MA, USA
16 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA
17 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA
18 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
; Bergthold, Guillaume 3 ; Pelton, Kristine 4 ; Becker, Sarah 4 ; Jones, Robert 4 ; Sinai, Claire E 5 ; Malkin, Hayley 6 ; Huang, Ying 4 ; Grimmet, Leslie 7 ; Herbert, Zachary T 7 ; Sun, Yu 6 ; Weatherbee, Jessica L 6 ; Alberta, John A 6 ; Daley, John F 8 ; Rozenblatt-Rosen, Orit 9 ; Condurat, Alexandra L 10 ; Kenin Qian 5 ; Khadka, Prasidda 6 ; Segal, Rosalind A 6 ; Haas-Kogan, Daphne 11 ; Filbin, Mariella G 10 ; Suva, Mario L 12
; Regev, Aviv 13 ; Stiles, Charles D 6 ; Kieran, Mark W 14 ; Goumnerova, Liliana 15
; Ligon, Keith L 16 ; Shalek, Alex K 17 ; Bandopadhayay, Pratiti 10 ; Beroukhim, Rameen 18
1 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA
2 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA
3 Hoffmann-La Roche, Product Development, Innovative Pediatric Oncology Drug Discovery, Basel, Switzerland; Centre Hospitalier Universitaire Strasbourg, Service Hématologie-Oncologie Pédiatrique, Strasbourg, France
4 Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA
5 Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA
6 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA
7 Molecular Biology Core Facilities, Dana-Farber Cancer Institute, Boston, MA, USA
8 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
9 Broad Institute of MIT and Harvard, Cambridge, MA, USA
10 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA
11 Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
12 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA
13 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Biology, Howard Hughes Medical Institute, Koch Institute, MIT, Cambridge, MA, USA
14 Department of Pediatric Oncology, Dana-Farber Boston Children’s Cancer and Blood Disorders Center, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA; Bristol-Myers Squibb, Boston, Devens, MA, USA; Bristol-Myers Squibb, Lawrenceville, NJ, USA
15 Department of Neurosurgery, Boston Children’s Hospital, Boston, MA, USA
16 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Oncologic Pathology, Dana Farber Cancer Institute, Boston, MA, USA
17 Broad Institute of MIT and Harvard, Cambridge, MA, USA; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA, USA
18 Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Pages
1-17
Publication year
2019
Publication date
Aug 2019
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2275917183
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.