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© 2018. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Kidney angiosarcomas usually metastasize from the skin, soft tissue, or visceral primary lesions, whereas primary renal angiosarcomas are rare. We report a case of primary renal angiosarcoma with morphological features similar to those of anastomosis hemangioma. Microscopically, there were multiple irregular anastomosing vascular spaces or channel‐like labyrinthine structures, and the tumor cells were positive for CD31, CD34, FLI‐1, PAX8, and vimentin; focally positive for factor VIII, CD10, and Ki‐67 (approximately 5%); and uniformly‐negative for CK, S‐100, and Melan‐A. The diagnosis of angiosarcoma depends on morphological and immunohistochemical examinations.

Details

Title
Primary renal angiosarcoma: A case report and literature review
Author
Xiao li Li 1 ; Tian, Xin 2 ; Guo, Jin 3 ; Zhang, Hong 4 ; Wang, Shuang 5 ; Shun dong Dai 1 

 Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, Liaoning, China 
 Molecular Oncology Laboratory of Cancer Research Institute, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China 
 Department of Toxicological Pathology, Safety Evaluation Center, Shenyang Research Institute of Chemical Industry, Shenyang, Liaoning, China 
 Department of Colorectal Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China 
 Department of Pathology, Shenyang Red Cross Hospital, Shenyang, Liaoning, China 
Pages
94-101
Section
CASE REPORT
Publication year
2018
Publication date
Sep 2018
Publisher
John Wiley & Sons, Inc.
e-ISSN
23987324
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2289562129
Copyright
© 2018. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.