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Abstract
A broader understanding was sought regarding the influence of specific adipose tissue depots on the isolated adipose-derived stem cell (ASC) populations through a systematic comparison of donor-matched abdominal subcutaneous fat and omentum, and donor-matched pericardial adipose tissue and thymic remnant samples. Results suggest that depot selection is an important factor to consider when applying ASCs in tissue-specific cell-based regenerative therapies, and also highlight pericardial adipose tissue as a potential new ASC source.
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Details
1 Department of Chemical Engineering, Queen's University, Kingston, Ontario, Canada; Human Mobility Research Centre, Kingston General Hospital, Kingston, Ontario, Canada
2 Department of Surgery, Kingston General Hospital, Kingston, Ontario, Canada
3 Department of Chemical Engineering, Queen's University, Kingston, Ontario, Canada; Human Mobility Research Centre, Kingston General Hospital, Kingston, Ontario, Canada; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada