Abstract
This phase I study evaluated the potential positive effect on bone regeneration by the addition of the freshly isolated, autologous but heterologous stromal vascular fraction (SVF) of adipose tissue. The study demonstrated for the first time the feasibility, safety, and potential efficacy of SVF seeded on bone substitutes for maxillary sinus floor elevation.
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1 Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), MOVE Research Institute Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands; Department of Oral and Maxillofacial Surgery, MOVE Research Institute Amsterdam, VU University Medical Center/ACTA, Amsterdam, The Netherlands
2 Department of Oral and Maxillofacial Surgery, MOVE Research Institute Amsterdam, VU University Medical Center/ACTA, Amsterdam, The Netherlands
3 Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), MOVE Research Institute Amsterdam, VU University Amsterdam, Amsterdam, The Netherlands
4 Department of Orthopedic Surgery, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, The Netherlands