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© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Luminescent europium-doped hydroxylapatite (EuXHAp) nanomaterials were successfully obtained by co-precipitation method at low temperature. The morphological, structural and optical properties were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier Transform Infrared (FT-IR), UV-Vis and photoluminescence (PL) spectroscopy. The cytotoxicity and biocompatibility of EuXHAp were also evaluated using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)) assay, oxidative stress assessment and fluorescent microscopy. The results reveal that the Eu3+ has successfully doped the hexagonal lattice of hydroxylapatite. By enhancing the optical features, these EuXHAp materials demonstrated superior efficiency to become fluorescent labelling materials for bioimaging applications.

Details

Title
Photoluminescent Hydroxylapatite: Eu3+ Doping Effect on Biological Behaviour
Author
Andronescu, Ecaterina; Predoi, Daniela; Neacsu, Ionela Andreea; Paduraru, Andrei Viorel; Musuc, Adina Magdalena; Trusca, Roxana; Oprea, Ovidiu; Tanasa, Eugenia; Vasile, Otilia Ruxandra; Nicoara, Adrian Ionut; Adrian Vasile Surdu; Iordache, Florin; Birca, Alexandra Catalina; Iconaru, Simona Liliana; Bogdan, Stefan Vasile
Publication year
2019
Publication date
Sep 2019
Publisher
MDPI AG
e-ISSN
20794991
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2302249916
Copyright
© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.