Abstract

Pacing tools that support small animals and can serve as models for pathogenesis of cardiovascular diseases are currently not available. Here, the authors report a miniaturized wireless battery-free implantable multimodal and multisite pacemaker that provides unlimited stimulation to test subjects.

Details

Title
Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models
Author
Gutruf, Philipp 1   VIAFID ORCID Logo  ; Yin, Rose T 2 ; Lee, K Benjamin 3 ; Ausra, Jokubas 4   VIAFID ORCID Logo  ; Brennan, Jaclyn A 2 ; Qiao, Yun 2 ; Xie, Zhaoqian 5   VIAFID ORCID Logo  ; Peralta, Roberto 6   VIAFID ORCID Logo  ; Talarico, Olivia 4 ; Murillo, Alejandro 2 ; Chen, Sheena W 2 ; Leshock, John P 7 ; Haney, Chad R 8   VIAFID ORCID Logo  ; Waters, Emily A 9   VIAFID ORCID Logo  ; Zhang, Changxing 10 ; Luan, Haiwen 11 ; Huang, Yonggang 11   VIAFID ORCID Logo  ; Trachiotis, Gregory 12 ; Efimov, Igor R 2   VIAFID ORCID Logo  ; Rogers, John A 13   VIAFID ORCID Logo 

 Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA; Center for Bio-Integrated Electronics at the Simpson Querrey Institute for BioNanotechnology and the Department of Materials Science and Engineering, Northwestern University, Evanston, IL, USA 
 Department of Biomedical Engineering, The George Washington University, Washington, DC, USA 
 Department of Biomedical Engineering, The George Washington University, Washington, DC, USA; Department of Surgery, The George Washington University, Washington, DC, USA 
 Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA 
 Department of Engineering Mechanics, Dalian University of Technology, Dalian, China; Department of Civil and Environmental Engineering, Mechanical Engineering, and Materials Science and Engineering, Northwestern University, Evanston, IL, USA 
 Department of Aerospace and Mechanical Engineering, University of Arizona, Tucson, AZ, USA 
 Department of Biomedical Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, USA 
 Center for Advanced Molecular Imaging, Radiology, and Biomedical Engineering, Northwestern University, Evanston, IL, USA 
 Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL, USA 
10  AML, Department of Engineering Mechanics, Interdisciplinary Research Center for Flexible Electronics Technology, Tsinghua University, Beijing, China 
11  Department of Civil and Environmental Engineering, Mechanical Engineering, and Materials Science and Engineering, Northwestern University, Evanston, IL, USA 
12  DC Veterans Affairs Medical Center, The George Washington University, Washington, DC, USA 
13  Departments of Materials Science and Engineering, Biomedical Engineering, Neurological Surgery, Chemistry, Mechanical Engineering, Electrical Engineering and Computer Science, Simpson Querrey Institute and Feinberg Medical School, Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL, USA 
Pages
1-10
Publication year
2019
Publication date
Dec 2019
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2327906418
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.