Abstract

The Z-ring, constituted of the tubulin homolog FtsZ protein, plays an essential role for bacterial cell division. Here the authors use an in vitro reconstitution approach to determine how the regulatory protein ZapA affects FtsZ treadmilling and filament organization into large-scale patterns.

Details

Title
Cooperative ordering of treadmilling filaments in cytoskeletal networks of FtsZ and its crosslinker ZapA
Author
Caldas, Paulo 1   VIAFID ORCID Logo  ; López-Pelegrín, Mar 1 ; Pearce, Daniel J G 2 ; Budanur, Nazmi Burak 1 ; Brugués, Jan 3   VIAFID ORCID Logo  ; Loose, Martin 1 

1  Institute of Science and Technology Austria, Klosterneuburg, Austria 
2  School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland 
3  Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany; Max Planck Institute for the Physics of Complex Systems, Dresden, Germany; Centre for Systems Biology Dresden, Dresden, Germany; Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany 
Pages
1-13
Publication year
2019
Publication date
Dec 2019
Publisher
Nature Publishing Group
e-ISSN
20411723
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41467-019-13702-4
ProQuest document ID
2327911038
Copyright
© 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.