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© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Deep-space travel is hazardous to astronauts because it exposes them to ionizing radiation in the forms of galactic cosmic rays (GCRs) and solar energetic particle events (SPEs). The present study was conducted in order to evaluate long term the effects 16O radiation on cognition, spine densities, dendrite complexity as well as the mRNA expression of glutamate receptors in the hippocampus. 2. [...]to the observation in the DG, no differences were found in the CA1 apical and basal area for total dendritic length (Apical t = 0.82, p = 0.43; Basal t = 0.85, p = 0.42), the number of branch points (Apical t = 0.34, p = 0.74; Basal t = 1.53, p = 0.16), branch tips (Apical t = 0.25, p = 0.80; Basal t = 1.34, p = 0.21; see Table 2), or the branch point complexity (Apical t = 0.64, p = 0.54; Basal t = 0.14, p = 0.88). [...]we conducted Sholl analyses in the hippocampal CA3.

Details

Title
Long-Term Changes in Cognition and Physiology after Low-Dose 16O Irradiation
Author
Howe, Alexis; Kiffer, Frederico; Alexander, Tyler C; Sridharan, Vijayalakshmi; Wang, Jing; Ntagwabira, Fabio; Rodriguez, Analiz; Boerma, Marjan; Allen, Antiño R
Publication year
2019
Publication date
2019
Publisher
MDPI AG
ISSN
16616596
e-ISSN
14220067
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2331889080
Copyright
© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.