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© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

[...]abnormalities in the properties of the ECMs may lead to loss of cellular homeostasis and functions. [...]ECM has been recently frequently incorporated into bone tissue engineering. According to the results of the previous study [35], we developed three-dimensional (3D) printed bioactive CS/PCL scaffolds by utilizing extrusion-based additive manufacturing technology, thus avoiding the use of any organic toxic solvents. The chemical decellularization procedure that was used in this study removed the intracellular content by piercing through the cellular membrane and allowed the removal of the intracellular contents [38]. [...]during the decellularization process, the cells shrank and became more sparsely distributed than those before undergoing decellularization [5].

Details

Title
3D-Printed Bioactive Calcium Silicate/Poly-ε-Caprolactone Bioscaffolds Modified with Biomimetic Extracellular Matrices for Bone Regeneration
Author
Yuan-Haw Andrew Wu; Yung-Cheng, Chiu; Yen-Hong, Lin; Chia-Che, Ho; Ming-You Shie; Yi-Wen, Chen
Publication year
2019
Publication date
2019
Publisher
MDPI AG
ISSN
16616596
e-ISSN
14220067
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2332040064
Copyright
© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.