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© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

[...]contact-active dental materials that inhibit the growth of acid-producing bacteria can potentially disturb and even correct the localized dysbiosis (imbalance) of the oral microflora that may lead to caries around dental sealants [8,9]. The main observable characteristics associated with S. mutans cariogenic pathogenicity include adhesion to tooth surfaces, synthesis of EPS via glucosyltransferases, biofilm formation, efficient use of sucrose to create an acidic environment, and aciduricity via acid tolerance response [13,20]. [...]this study aimed to investigate the effect of sealant formulations with 5% DMAHDM and 20% NACP on the virulence properties and viability of S. mutans biofilms. 2. Analysis of the lactic acid concentration indicates a significant effect of DMAHDM incorporation (F1,40 = 4.611, P = 0.027) on the biofilm lactic acid production.

Details

Title
A Novel Dental Sealant Containing Dimethylaminohexadecyl Methacrylate Suppresses the Cariogenic Pathogenicity of Streptococcus mutans Biofilms
Author
Maria Salem Ibrahim; Ibrahim, Ahmed S; Balhaddad, Abdulrahman A; Weir, Michael D; Lin, Nancy J; Tay, Franklin R; Oates, Thomas W; Xu, Hockin H K; Melo, Mary Anne S
Publication year
2019
Publication date
2019
Publisher
MDPI AG
ISSN
16616596
e-ISSN
14220067
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2333600531
Copyright
© 2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.