Abstract

Background: Lycium chinense fruit (LCF) is widely distributed in East Asia that has been used traditionally for antiaging purposes. This study was performed to examine the effects of LCF on attention and cognitive function in healthy young people. Materials and Methods: An 11-week, double-blind, randomized, placebo-controlled, crossover trial of 74 patients was conducted and its data were collected on Kyung-Hee University Korean Medical Hospital, Seoul, Korea. In crossover treatment, LCF or placebo was administered three times a day, total 3600 mg as two capsules of 600 mg once for 4 weeks with 3-week washout each. The computerized neurocognitive function test (CNT), the Korean version of the attention-deficit/hyperactivity disorder rating scale-IV, the clinical global impression rating scale, and the Frankfurt attention inventory (FAIR) for two groups were conducted 0 week before and 4 week, 11 week after the experiment, and significant mean changes of these tests for within group or two groups were measured by paired t-test or unpaired t-test. Results: The administration of LCF or placebo crossover for 8 weeks in healthy young people presented significant improvement in the verbal learning test, digit span forward test, digit span backward test, auditory continuous performance task of CNT, and FAIR-performance value compared with the placebo group (each group n = 43, P < 0.05). Conclusion: Thus, the consumption of LCF might be beneficial to increase learning and memory through attention and cognitive enhancing effect in normal young people, at an average age of 18 years of age.

Details

Title
Standardized Lycium chinense fruit extract enhances attention and cognitive function in healthy young people by a double-blind, randomized, placebo-controlled, crossover trial
Author
Sun-Yong, Chung 1 ; Kang, Moonkyu 2 ; Seong-Bin, Hong 3 ; Bae, Hyunsu 2 ; Cho, Seung-Hun 1 

 Department of Neuropsychiatry, College of Korean Medicine, Kyung-Hee University, Seoul 
 Department of Physiology, College of Korean Medicine, Kyung-Hee University, Seoul 
 Biomix Inc. 142 Ilsan-ro, Isandong-gu, Koyang, Kyunggi-do 
Pages
102-102
Publication year
2019
Publication date
Jan-Dec 2019
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
17351995
e-ISSN
17357136
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2334103418
Copyright
© 2019. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.