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Copyright © 2020 Peiyao Wu et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. http://creativecommons.org/licenses/by/4.0/

Abstract

Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disorder mediated by T cells, with a multifactorial etiology. Hashimoto’s thyroiditis (HT) is a common autoimmune disease characterized by hypothyroidism. Although many clinical studies conducted over the past several decades have reported the cooccurrence of OLP and HT, the underlying mechanism remains unclear. This review summarizes potential mechanisms that might be involved in the cooccurrence of OLP and HT. We find that OLP and HT share a common or overlapping pathogenesis in terms of immune, heredity, environmental, and hormonal factors, which might cause cooccurrence. Furthermore, considering the latency of HT, a routine screen for thyroid diseases, particularly HT, is suggested for confirmed OLP patients.

Details

Title
Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto’s Thyroiditis
Author
Wu, Peiyao  VIAFID ORCID Logo  ; Luo, Shuhan; Zhou, Tao; Wang, Rui; Qiu, Xuemei; Yuan, Peiyang; Yang, Yuqing; Han, Qi  VIAFID ORCID Logo  ; Lu, Jiang  VIAFID ORCID Logo 
Editor
Cristina Contreras
Publication year
2020
Publication date
2020
Publisher
John Wiley & Sons, Inc.
ISSN
09629351
e-ISSN
14661861
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2355830627
Copyright
Copyright © 2020 Peiyao Wu et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. http://creativecommons.org/licenses/by/4.0/