Abstract

Hookworms are intestinal parasites that cause major public health problems, especially in developing countries. To differentiate eggs from different hookworm species, it is necessary to use molecular methodologies, since the eggs are morphologically similar. Here, we performed the molecular identification of single hookworm eggs from six Brazilian states. Of the 634 eggs individually analyzed, 98.1% (622/634) represented Necator americanus, and surprisingly, 1.9% (12/634 eggs from the same patient) represented Ancylostoma caninum. DNA analysis of the A. caninum-positive stool sample revealed no contamination with animal feces. This is the first report of the presence of A. caninum eggs in human feces, which may have a direct implication for the epidemiology of hookworm infection caused by this species. This suggests the need for special attention regarding prophylaxis, as different reservoirs, previously not described, may have great relevance for the spread of A. caninum.

Details

Title
Egg genotyping reveals the possibility of patent Ancylostoma caninum infection in human intestine
Author
Furtado Luis Fernando Viana 1 ; Dias Lucas Teixeira de Oliveira 2 ; Rodrigues Thais de Oliveira 2 ; Silva Vivian Jordania da 2 ; Oliveira Valéria Nayara Gomes Mendes de 2 ; Rabelo Élida Mara Leite 2 

 Universidade do Estado de Minas Gerais, Avenida Juca Stockler, 1130, CEP 37900-106, Passos, Brazil (GRID:grid.442085.f) 
 Universidade Federal de Minas Gerais, Instituto de Ciências Biológicas, Avenida Presidente Antônio Carlos, 6627, Departamento de Parasitologia, L4 237, Laboratório de Parasitologia Molecular, Pampulha, CEP 31270-901, Belo Horizonte, Brazil (GRID:grid.8430.f) (ISNI:0000 0001 2181 4888) 
Publication year
2020
Publication date
2020
Publisher
Nature Publishing Group
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2359373138
Copyright
This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.