Abstract

Chelates are used in cancer as cytotoxic agent, as radioactive agent in imaging studies and in radioimmunotherapy. Various chelates based on ruthenium, copper, zinc, organocobalt, gold, platinum, palladium, cobalt, nickel and iron are reported as cytotoxic agent. Monoclonal antibodies labeled with radioactive metals such as yttrium-90, indium-111 and iodine-131 are used in radioimmunotherapy. This review is an attempt to compile the use of chelates as cytotoxic drugs and in radioimmunotherapy.

Details

Title
Role of chelates in treatment of cancer
Author
Tripathi, Laxmi; Kumar, Praveen; Singhai, A
Pages
62-71
Publication year
2007
Publication date
2007
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
0019509X
e-ISSN
19984774
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
236496562
Copyright
Copyright Medknow Publications 2007