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Abstract

Four fucosterol derivatives were isolated from the ethyl acetate fraction of Hizikia fusiformis. The chemical structures of the sterols were elucidated as fucosterol (1), a mixture of 24R,28R- and 24S,28R-epoxy-24-ethylcholesterol at the ratio of 3 to 2 (2), and 24R-saringosterol (3), all of which exhibited proliferation activity on MG63 cells.

Details

Title
Fucosterols from Hizikia fusiformis and their proliferation activities on osteosarcoma-derived cell MG63
Author
Gyu-Won, Huh 1 ; Dae-Young, Lee 1 ; In Suh-Ji 1 ; Don-Gil, Lee 1 ; Park, Sang Yong 1 ; Tae-Hoo, Yi 1 ; Kang, Hee Cheol 2 ; Woo-Duck, Seo 3 ; Baek Nam-In 1 

 Kyung Hee University, The Graduate School of Biotechnology and Department of Oriental Medicinal Materials & Processing, Yongin, Republic of Korea (GRID:grid.289247.2) (ISNI:0000000121717818) 
 GFC Co., Ltd., Suwon, Republic of Korea (GRID:grid.289247.2) 
 National Institute of Crop Science, RDA, Department of Functional Crop, Milyang, Republic of Korea (GRID:grid.289247.2) 
Pages
551-555
Publication year
2012
Publication date
Aug 2012
Publisher
Springer Nature B.V.
ISSN
17382203
e-ISSN
2234344X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2399162520
Copyright
© The Korean Society for Applied Biological Chemistry 2012.