Abstract

The subject of analysis is the male skeleton from a double burial of the Globular Amphora Culture, derived from the Neolithic site at Brześć Kujawski in Kujawy region (central Poland). Within the spine of the individual advanced lesions are observed (destruction of the vertebral bodies, symptoms of the periostitis in the thoracic region) which are characteristic of skeletal tuberculosis. To check whether the observed morphological changes resulted from infection with Mycobacterium tuberculosis (M.tb), the bone material was tested positively for the presence of mycolic acids, the specific components of the cell wall of pathogenic M.tb bacilli, by mass spectrometry.

Details

Title
Mycolic Acids as Markers of Osseous Tuberculosis in the Neolithic Skeleton from Kujawy Region (Central Poland)
Author
Borowska-Strugiń, Beata 1 ; Druszczyńska, Magdalena 2 ; Lorkiewicz, Wiesław 1 ; Szewczyk, Rafał 3 ; Ządzińska, Elzbieta 1 

 Department of Anthroplogy, Faculty of Biology ad Environmental Protection, University of Łódź, Poland 
 Department of Immunology and Infectious Biology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland 
 Department of Biotechnology and Industrial Microbiology, Institute of Microbiology, Biotechnology and Immunology, Faculty of Biology ad Environmental Protection, University of Łódź, Poland 
Pages
137-149
Publication year
2014
Publication date
2014
Publisher
University of Łódź
ISSN
18986773
e-ISSN
20834594
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2406885213
Copyright
© 2014. This work is published under http://creativecommons.org/licenses/by-nc-nd/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.