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Copyright © 2015 Chiara Dobrinja et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Background. Radiofrequency ablation (RFA) has been recently advocated as an effective technique for the treatment of symptomatic benign thyroid nodules. It is not known to what extent it may affect any subsequent thyroid surgery and/or histological diagnosis. Materials and Methods. RFA was performed on 64 symptomatic Thy2 nodules (benign nodules) and 6 symptomatic Thy3 nodules (follicular lesions/follicular neoplasms). Two Thy3 nodules regrew after the procedure, and these patients accepted to undergo a total thyroidectomy. Here we present how RFA has affected the operation and the final pathological features of the surgically removed nodules. Results and Conclusions. RFA is effective for the treatment of Thy2 nodules, but it should not be recommended as first-line therapy for the treatment of Thy3 nodules (irrespective of their mutational status), as it delays surgery in case of malignancy. Moreover, it is unknown whether RFA might promote residual tumor progression or neoplastic progression of Thy3 lesions. Nevertheless, here we show for the first time that one session of RFA does not affect subsequent thyroid surgery and/or histological diagnosis.

Details

Title
Surgical and Pathological Changes after Radiofrequency Ablation of Thyroid Nodules
Author
Dobrinja, Chiara 1 ; Bernardi, Stella 2   VIAFID ORCID Logo  ; Fabris, Bruno 2 ; Eramo, Rita 1 ; Makovac, Petra 1 ; Bazzocchi, Gabriele 3 ; Piscopello, Lanfranco 4 ; Barro, Enrica 2 ; de Manzini, Nicolò 1   VIAFID ORCID Logo  ; Bonazza, Deborah 5 ; Pinamonti, Maurizio 5 ; Zanconati, Fabrizio 5 ; Stacul, Fulvio 3 

 UCO Chirurgia Generale, Cattinara Teaching Hospital, Strada di Fiume, 34100 Trieste, Italy 
 SS Endocrinologia (UCO Medicina Clinica), Cattinara Teaching Hospital, Strada di Fiume, 34100 Trieste, Italy 
 SC Radiologia, Maggiore Hospital, Piazza dell’Ospitale, 34100 Trieste, Italy 
 SS Endocrinologia (III Medica), Maggiore Hospital, Piazza dell’Ospitale, 34100 Trieste, Italy 
 Department of Medical, Surgical, and Health Sciences, University of Trieste, Cattinara Teaching Hospital, Strada di Fiume, 34100 Trieste, Italy 
Editor
Jack R Wall
Publication year
2015
Publication date
2015
Publisher
John Wiley & Sons, Inc.
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2411095162
Copyright
Copyright © 2015 Chiara Dobrinja et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.