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Abstract
The purpose of this randomized clinical trial is to evaluate the effect of eyelid hygiene on subjective symptoms, anterior blepharitis, and meibomian gland dysfunction (MGD) after cataract surgery. Subjects with obstructive MGD who underwent cataract surgery were randomly divided into two groups. In the eyelid hygiene group, eyelid hygiene was performed twice a day for 10 days from 3 days before to 1 week after cataract surgery. The control group did not perform eyelid hygiene. A subjective symptom questionnaire of SPEED, anterior blepharitis grade, and meibum quality and quantity was evaluated at baseline and at postoperative 1 and 4 weeks. The eyelid hygiene group (n = 36) showed decreased SPEED score after cataract surgery and the control group (n = 33) did not. Anterior blepharitis grade was worse 1 week after surgery in the control group but not in the eyelid hygiene group. The control group had significantly decreased meibum quality and quantity in both the upper and lower eyelids after cataract surgery, but the eyelid hygiene group did not. Eyelid hygiene before/after cataract surgery improved postoperative subjective symptoms and prevented postoperative exacerbation of anterior blepharitis and MGD. Thus, perioperative eyelid hygiene is recommended for patients with obstructive MGD who undergo cataract surgery.
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1 Korea University College of Medicine, Department of Ophthalmology, Korea University Ansan Hospital, Gyeonggi-do, South Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.222754.4)
2 The Catholic University of Korea, Department of Ophthalmology, Yeouido St. Mary’s Hospital, College of Medicine, Seoul, South Korea (GRID:grid.411947.e) (ISNI:0000 0004 0470 4224); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.411947.e)
3 Dankook University College of Medicine, Department of Ophthalmology, Cheonan, South Korea (GRID:grid.411982.7) (ISNI:0000 0001 0705 4288); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.411982.7)
4 Sungkyunkwan University School of Medicine, Department of Ophthalmology, Samsung Medical Center, Seoul, South Korea (GRID:grid.264381.a) (ISNI:0000 0001 2181 989X); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.264381.a)
5 Ewha Woman’s University School of Medicine, Department of Ophthalmology, Seoul, South Korea (GRID:grid.255649.9) (ISNI:0000 0001 2171 7754); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.255649.9)
6 Konyang University College of Medicine, Department of Ophthalmology, Daejeon, Republic of Korea (GRID:grid.411143.2) (ISNI:0000 0000 8674 9741); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.411143.2)
7 Chung-Ang University College of Medicine, Department of Ophthalmology, Chung-Ang University Hospital, Seoul, South Korea (GRID:grid.254224.7) (ISNI:0000 0001 0789 9563); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.254224.7)
8 The Catholic University of Korea, Department of Ophthalmology, Seoul St. Mary’s Hospital, College of Medicine, Seoul, South Korea (GRID:grid.411947.e) (ISNI:0000 0004 0470 4224); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.411947.e)
9 Korea University College of Medicine, Department of Ophthalmology, Korea University Guro Hospital, Seoul, South Korea (GRID:grid.222754.4) (ISNI:0000 0001 0840 2678); Korean Meibomian gland & Ocular Surface study group, Seoul, South Korea (GRID:grid.222754.4)