Abstract

A few years later, he developed anxiety, panic attacks and time obsession. Since behavioral and phasic disturbances progressivly appeared, he was referred to a department of neurology at the age of 24. The other hemisphere was cut into coronal sections and kept at − 80 °C. A small piece of frontal cortex was fixed in 4% glutaraldehyde for transmission electron microscopy. SEE PDF] The ultrastructural aspect of the tau inclusions was analysed on ultrathin sections by transmission electron microscopy (Fig. 1o).

Details

Title
de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia
Author
Ando, Kunie; Ferlini, Lorenzo; Suain, Valérie; Yilmaz, Zehra; Mansour, Salwa; Isabelle Le Ber; Bouchard, Cécile; Karelle Leroy; Durr, Alexandra; Clot, Fabienne; Sarazin, Marie; Bier, Jean-Christophe; Brion, Jean-Pierre  VIAFID ORCID Logo 
Pages
1-4
Section
Letter to the Editor
Publication year
2020
Publication date
2020
Publisher
BioMed Central
e-ISSN
20515960
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s40478-020-00977-8
ProQuest document ID
2424705903
Copyright
© 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.