Full Text

Turn on search term navigation

© 2020. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Aims

The long‐term impact of coffee or tea consumption on subclinical left ventricular (LV) systolic or diastolic function has not been previously studied. We examined the association between coffee or tea consumption beginning in early adulthood and cardiac function in midlife.

Methods and results

We investigated 2735 Coronary Artery Risk Development in Young Adults (CARDIA) study participants with long‐term total caffeine intake, coffee, and tea consumption data from three visits over a 20 year interval and available echocardiography indices at the CARDIA Year‐25 exam (2010–2011). Linear regression models were used to assess the association between caffeine intake, tea, and coffee consumption (independent variables) and echocardiography outcomes [LV mass, left atrial volume, and global longitudinal strain (GLS), LV ejection fraction (LVEF), and transmitral Doppler early filling velocity to tissue Doppler early diastolic mitral annular velocity (E/e´)]. Models were adjusted for standard cardiovascular risk factors, socioeconomic status, physical activity, alcohol use, and dietary factors (calorie intake, whole and refined grain intake, and fruit and vegetable consumption). Mean (standard deviation) age was 25.2 (3.5) years at the CARDIA Year‐0 exam (1985–1986), 57.4% were women, and 41.9% were African‐American. In adjusted multivariable linear regression models assessing the relationship between coffee consumption and GLS, beta coefficients when comparing coffee drinkers of <1, 1–2, 3–4, and >4 cups/day with non‐coffee drinkers were β = −0.30%, P < 0.05; β = −0.35%, P < 0.05; β = −0.32%, P < 0.05; β = −0.40%, P > 0.05; respectively (more negative values implies better systolic function). In adjusted multivariable linear regression models assessing the relationship between coffee consumption and E/e´, beta coefficients when comparing coffee drinkers of <1, 1–2, 3–4, and >4 cups/day with non‐coffee drinkers were β = −0.29, P < 0.05; β = −0.38, P < 0.01; β = −0.20, P > .05; and β = −0.37, P > 0.05, respectively (more negative values implies better diastolic function). High daily coffee consumption (>4 cups/day) was associated with worse LVEF (β = −1.69, P < 0.05). There were no associations between either tea drinking or total caffeine intake and cardiac function (P > 0.05 for all).

Conclusions

Low‐to‐moderate daily coffee consumption from early adulthood to middle age was associated with better LV systolic and diastolic function in midlife. High daily coffee consumption (>4cups/day) was associated with worse LV function. There was no association between caffeine or tea intake and cardiac function.

Details

Title
Coffee and tea consumption in the early adult lifespan and left ventricular function in middle age: the CARDIA study
Author
Nwabuo, Chike C. 1 ; Betoko, Aisha S. 1 ; Reis, Jared P. 2 ; Moreira, Henrique T. 3 ; Vasconcellos, Henrique D. 1 ; Guallar, Eliseo 1 ; Cox, Christopher 1 ; Sidney, Stephen 4 ; Ambale‐Venkatesh, Bharath 1 ; Lewis, Cora E. 5 ; Schreiner, Pamela J. 6 ; Lloyd‐Jones, Donald 7 ; Kiefe, Catarina I. 8 ; Gidding, Samuel S. 9 ; Lima, João A.C. 1 

 Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA 
 National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA 
 Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA, Ribeirão Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil 
 Division of Research, Kaiser Permanente, Oakland, CA, USA 
 School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA 
 School of Public Health, University of Minnesota, Minneapolis, MN, USA 
 Feinberg School of Medicine, Northwestern University, Chicago, IL, USA 
 Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA 
 Nemours Cardiac Center, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA 
Pages
1510-1519
Section
Original Research Articles
Publication year
2020
Publication date
Aug 1, 2020
Publisher
John Wiley & Sons, Inc.
e-ISSN
20555822
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2425759606
Copyright
© 2020. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.