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Abstract
A possible hypothesis might be that the upper respiratory tract is attacked by viruses which are breathed in and coughed up in sputum while the lower respiratory tract is similarly infected, but is also attacked at the same time by blood-borne viruses (following translocation from a significant viral load in the gastrointestinal tract). (For MERS-CoV, treatment with a proton pump inhibitor in an animal model resulted in exaggerated infection in the small intestine [4].) [...]they may not appear on a list of a patient’s usual medications.
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