Response to important considerations when assessing the effect of essential fatty acids on cognitive performance

Abstract

In this letter, we respond to the comments raised by Visaria et al. in their letter to the editor about the publication “Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: National Health and Nutrition Examination Survey (NHANES) 2011–2014”. We have further adjusted for some key covariates as the authors mentioned in the letter and performed sensitivity analysis by excluding vegetarians considering the bioavailability of fatty acids from different sources. In conclusion, the results were basically consistent with our previous results, which showed that the results were stable and reliable. We hope that our study could be helpful in further studies delineating the various intricacies of fatty acid nutrition and metabolism and control for covariates.