A Corrigendum on
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
by Lu, D.-S., Chen, C., Zheng, Y.-X., Li, D.-D., Wang, G.-Q., Liu, J., et al. (2018). Front. Mol. Neurosci. 11:155. doi: 10.3389/fnmol.2018.00155
In the original article, there was a mistake in Figure 6 as published. One western blot band of β-actin corresponding to TNF-α protein level 21 days after daily L-DOPA combined with ICA treatment in Figure 6B was inserted incorrectly. The corrected Figure 6 appears below.
FIGURE 6
![View Image - Figure 6. ICA inhibited the neuroinflammation in LID after 6-OHDA-induced DA neuronal damage. The protein levels of neuroinflammatory factors, such as COX-2, IL-1[beta] and TNF-[alpha], in the SN were detected 7 (A) and 21 (B) days after daily L-DOPA (25 mg/kg, i.p.) combined with ICA (20 mg/kg, p.o.) treatment by western blotting. Data were shown as mean ± SEM from six rats (n = 6). *p < 0.05 compared with the control group; #p < 0.05 compared with 6-OHDA-treated group; Ψp < 0.05 compared with 6-OHDA+L-DOPA group.](https://media.proquest.com/media/hms/THUM/2/tcHSH?_a=ChgyMDI1MDcwNzAxNTQ1ODE1MDo0OTE5MDMSBzEzODMzMjMaCk9ORV9TRUFSQ0giDTIxNi43My4yMTYuNjgqBzIwNDY0NTcyCjI0NTU2NDYxNzM6C0lubGluZUltYWdlQgEwUgZPbmxpbmVaA0lMSWIEVEhVTWoKMjAyMC8xMC8yOXIKMjAyMC8xMC8yOXoAggEgUC0xMDAwMDg0LTIwMTM5NS1TVEFGRi1udWxsLW51bGySAQZPbmxpbmXKAWdNb3ppbGxhLzUuMCBBcHBsZVdlYktpdC81MzcuMzYgKEtIVE1MLCBsaWtlIEdlY2tvOyBjb21wYXRpYmxlOyBDbGF1ZGVCb3QvMS4wOyArY2xhdWRlYm90QGFudGhyb3BpYy5jb20p0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCG09TOkVNUy1GdWxsVGV4dC1nZXRGdWxsVGV4dMoCFUNvcnJlY3Rpb24vUmV0cmFjdGlvbuICAPICAPoCAVmCAwNXZWKKAxxDSUQ6MjAyNTA3MDcwMTU0NTgxNTA6ODQzMzI0&_s=X5oArSyHUGkFItUi1XnHUdM3uc8%3D "View Image - Figure 6. ICA inhibited the neuroinflammation in LID after 6-OHDA-induced DA neuronal damage. The protein levels of neuroinflammatory factors, such as COX-2, IL-1[beta] and TNF-[alpha], in the SN were detected 7 (A) and 21 (B) days after daily L-DOPA (25 mg/kg, i.p.) combined with ICA (20 mg/kg, p.o.) treatment by western blotting. Data were shown as mean ± SEM from six rats (n = 6). *p < 0.05 compared with the control group; #p < 0.05 compared with 6-OHDA-treated group; Ψp < 0.05 compared with 6-OHDA+L-DOPA group.")
Enlarge this image.Figure 6. ICA inhibited the neuroinflammation in LID after 6-OHDA-induced DA neuronal damage. The protein levels of neuroinflammatory factors, such as COX-2, IL-1[beta] and TNF-[alpha], in the SN were detected 7 (A) and 21 (B) days after daily L-DOPA (25 mg/kg, i.p.) combined with ICA (20 mg/kg, p.o.) treatment by western blotting. Data were shown as mean ± SEM from six rats (n = 6). *p < 0.05 compared with the control group; #p < 0.05 compared with 6-OHDA-treated group; Ψp < 0.05 compared with 6-OHDA+L-DOPA group.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Di-Sheng Lu†, Ce Chen†, Ya-Xin Zheng†, Dai-Di Li, Guo-Qing Wang, Jie Liu, Jingshan Shi and Feng Zhang*
* Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China
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