Abstract

We present revised diagnostic and therapeutic guidelines for the management of pancreatic neuroendocrine neoplasms (PNENs) proposed by the Polish Network of Neuroendocrine Tumours.These guidelines refer to biochemical (determination of specific and nonspecific neuroendocrine markers) and imaging diagnostics (EUS, CT, MR, and radioisotope examination with a 68Ga or 99Tc labelled somatostatin analogue).A histopathological diagnostic, which determines the further management of patients with PNENs, must be necessarily confirmed by immunohistochemical tests. PNENs therapy requires collaboration between a multidisciplinary team of specialists experienced in the management of these neoplasms. Surgery is the basic form of treatment. Medical therapy requires a multidirectional procedure, and therefore the rules of biotherapy, peptide receptor radionuclide therapy, chemotherapy and molecular targeted therapy are discussed. (Endokrynol Pol 2013; 64 (6): 459–479)

Details

Title
Pancreatic neuroendocrine neoplasms — management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)
Author
Kos-Kudła, Beata 1 ; Hubalewska-Dydejczyk, Alicja; Kuśnierz, Katarzyna; Lampe, Paweł; Marek, Bogdan; Nasierowska-Guttmejer, Anna; Nowakowska-Duława, Ewa; Pilch-Kowalczyk, Joanna; Sowa-Staszczak, Anna; Rosiek, Violetta; participants of the Consensus Conference (affiliations at the end of this section):, Other; Andrysiak-Mamos, Elżbieta; Bednarczuk, Tomasz; Blicharz-Dorniak, Jolanta; Bolanowski, Marek; Cichocki, Andrzej; Ćwikła, Jarosław B.; Deptała, Andrzej; Foltyn, Wanda; Handkiewicz-Junak, Daria; Hartleb, Marek; Jarząb, Michał; Jeziorski, Arkadiusz; Kajdaniuk, Dariusz; Kamiński, Grzegorz; Kowalska, Aldona; Król, Robert; Królicki, Leszek; Kunikowska, Jolanta; Lange, Dariusz; Lewczuk, Anna; Londzin-Olesik, Magdalena; Majewski, Przemysław; Mełeń-Mucha, Gabriela; Nowak, Andrzej; Patkowski, Waldemar; Ruchała, Marek; Rudzki, Sławomir; Ruszniewski, Philippe; Rydzewska, Grażyna; Starzyńska, Teresa; Steinhof-Radwańska, Katarzyna; Strzelczyk, Janusz; Zajęcki, Wojciech; Zdunowski, Piotr; Zemczak, Anna

1  Division of Endocrinology, Department of Pathophysiology and Endocrinology, Medical University of Silesia, Katowice, Poland. [email protected] 
First page
459
End page
479
Publication year
2013
Publication date
2013
Publisher
Wydawnictwo Via Medica
ISSN
0423104X
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.5603/EP.2013.0031
ProQuest document ID
2464206556
Copyright
© 2013. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.